Category: Atherosclerosis

Two-Hour After-meal high blood sugar predicts Atherosclerosis better than Fasting blood sugar and HbA1c

Posted on by Jesse Santiano, M.D.

This article presents a study that showed the best blood test to predict the development of atherosclerosis. One thousand eight hundred fifty-two patients scheduled for coronary angiography were classified into Normal Glucose Tolerance (NGT), Impaired Glucose Regulation (IGR), and diabetes based on Fasting blood sugar, Post-prandial blood glucose (PBG), and Hemoglobin A1c (HbA1c).[1] Blood Sugar…

Testing Post Prandial Glucose Level after a Feast

Posted on by Jesse Santiano, M.D.

This article is about the result of a technique to lower post-prandial blood sugar. After-meal glucose spikes or post-prandial hyperglycemia leads to atherosclerosis formation. Atherosclerosis can happen to anyone, even if they do not have diabetes. Post-prandial hyperglycemia predicts atherosclerosis formation better than fasting blood sugar and hemoglobin A1c. Read about it at After meal…

High blood sugar causes Metabolic Memory

Posted on by Jesse Santiano, M.D.

This article presents a study that showed that high blood sugar could change macrophages and cause atherosclerosis. The study was published in the journal Circulation in Sept 2021. The authors are from Oxford, UK; the Karolinska Institute in Sweden, the Radboud University in the Netherlands; and the Life and Medical Sciences Institute (LIMES) at the…

A Healthy Lifestyle is as effective as Voglibose and Nateglinide in Lowering 10-year Cardiac Mortality

Posted on by Jesse Santiano, M.D.

This article presents two studies that show the superiority of a healthy lifestyle in lowering cardiac-related deaths compared to diabetes medications. And second, the importance of managing early diabetes to prevent cardiovascular deaths. The first study, Effects of voglibose and nateglinide on glycemic status and coronary atherosclerosis in early-stage diabetic patients, or the DIANA (DIAbetes…

Intermittent fasting Reverses Endothelial Dysfunction

Posted on by Jesse Santiano, M.D.

This article presents three studies showing intermittent fasting could improve endothelial function. The endothelium is the inner lining of the blood vessels, and the cells in it do a full-time job of keeping it smooth, distensible, and open to maintain adequate organ perfusion, and lower blood pressure, resulting in less work for the heart. The…

After meal blood sugar spikes as a cause of vascular failure

Posted on by Jesse Santiano, M.D.

This article is about the damaging effects of high blood sugar on the blood vessels after a meal. Post Prandial Hyperglycemia Post-prandial hyperglycemia (PPH) is the medical term for increased blood sugar after eating. It occurs if the blood sugar is 140 – 200 mg/dl two hours after eating. PPH can damage the arteries. The…

How to Prevent Hyperglycemia with the Vegetables-Meat-Carbs Sequence

Posted on by Jesse Santiano, M.D.

This article presents a study that shows how to prevent the rapid rise of blood sugar after a meal or Post-Prandial Glycemia (PPG) After-Meal Blood Sugar and atherosclerosis High blood sugar after meals is a risk factor for developing diabetes and atherosclerosis. It injures the inner lining of the arteries and starts or continues atherosclerosis.[1]…