Increased risk of Stroke with Same Time Influenza and COVID-19 Vaccination

Fall is coming soon, which is the time for influenza shots to be recommended. And since the patients are already in their doctor’s offices, most likely, you will be offered a COVID-19 booster, too.

Why not? It saves you a trip, right?

They may even quote you this new preprint study. Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses, concluding that simultaneous administration of these vaccines may yield higher and more durable SARS-CoV-2 antibody responses.

And since the authors are from the Massachusetts General Hospital, Harvard, and MIT, it must be a good study with correct conclusions, and you should go ahead and get two shots in one visit.

But before you do that, take a look at this CDC report about the incidence of ischemic stroke after getting the flu and COVID-19 shot at the same time.

Especially if you are ≥65 and the flu shot is a high-dose or adjuvanted flu vaccine. See the Adjusted rate ratio of 1.59 that I marked in a red rectangle.

Source: Tom T. Shimabukoro, Centers for Disease Control and Prevention (CDC). (2023, April 19). COVID-19 Vaccine Safety Update: April 2023 [PDF slides]. Retrieved from
https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-04-19/03-COVIDShimabukuro-508.pdf [accessed 9.11.23] page 14
A rate ratio of 1.59 means a 59% increased rate of having an ischemic stroke.

In contrast, there is no increased risk with the standard flu vaccine, and according to this CDC report, there is none if the bivalent Pfizer is given alone.

However, a study already showed an increased risk of stroke after the bivalent COVID-19 shot. I wrote about it at Higher Risk of Strokes after the Pfizer Bivalent Jabs.

Read more about risk ratios at this link.

Now I don’t know why there is nothing about this in the news. If Pfizer is your advertiser, you don’t want to bite the hands that feed you.

Don’t Have a Stroke!

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References: 

  1. Susanna E BarouchTaras M ChiczRoss BlancDomenic R BarbatiLily J ParkerXin TongRyan P McNamara. Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses. bioRxiv 
  2. Tom T. Shimabukoro, Centers for Disease Control and Prevention (CDC). (2023, April 19). COVID-19 Vaccine Safety Update: April 2023 [PDF slides]. Retrieved from
    Tom T. Shimabukoro, Centers for Disease Control and Prevention (CDC). (2023, April 19). COVID-19 Vaccine Safety Update: April 2023 [PDF slides]. Retrieved from
    https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-04-19/03-COVIDShimabukuro-508.pdf [accessed 9.11.23] [accessed 9.14.23]

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