Never Give Up—Fight Illness With Strength And Science
Intermittent fasting, fasting, sleep, chronotherapy, circadian rhythm, life extension, nattokinase, staying fit, resistance training, myokines, life entension, neuroscience,
Updated on November 30, 2025, with new Latin American Spanish and Mandarin audio versions to help readers worldwide access this content. 🎧 ▶️ Press the play button below to listen in English. 🇨🇳 中文（简体） 请按下方的播放按钮收听。 This article is Round 3 of Intermittent Fasting (I.F.) vs. Sulfonylureas Recap: Round 1 went to I.F. because it protects…
What is Sulfonulyrea? Sulfonylureas are prescribed for Type 2 diabetes. The common ones are glyburide, glibenclamide, glipizide, and glimepiride. How Do Sulfonylureas Work? Sulfonylureas work by making the beta cells of the pancreas release more insulin. Why Do You Need Sulfonylureas for that? Isn’t Insulin Release Normal and Automatic? Usually, when the body senses a…
Alzheimer’s and Parkinson’s disease are examples of neurodegenerative diseases. They are similar to coronary artery disease, diabetes, hypertension, and obesity in that they all result from chronic inflammation. The diseases mentioned above are also associated with chronic lack of sleep. Sleep time is when the body repairs itself. It is also the period with the…
Melatonin has a profound influence on health. The article, Wake-Up to the Other Benefits Melatonin, the other benefits of melatonin in preventing cardiovascular disease, neurodegenerative disease, obesity, diabetes, and cancer were listed. The problem with endogenous melatonin is that melatonin secretion from the pineal gland declines as people get older, and this may explain the…
Melatonin is known as the “sleep hormone.” Sleep is essential for health, and many common disorders are associated with poor sleep. Could it be because lack of sleep also deprives the body of the other lesser-known benefits of melatonin? This article lists many other bioactivities of melatonin on human and animal studies. Bioactivities of Melatonin…
Question: “Jess, How about exogenous melatonin daily?” That is from Dr. N.B., my good friend from college and medical school. To answer this question, I searched the National Library of Medicine on the internet. The most complete answer about melatonin safety was from research in 2000 to assess the safety of the chronic use of…
What is Allergic Rhinitis? Allergic Rhinitis is the reaction of the upper airway, including the nose to allergens. The source of the allergies can be dust, mites, spores, pollen, animal dander, and saliva. The symptoms are sneezing, runny nose, nasal itchiness, and congestion. The Circadian (Day-Night) Pattern of Allergic Rhinitis Many surveys have shown that…
Bottom line: Anytime as long as it ensures compliance. HMG-CoA reductase inhibitors, commonly known as statins, which are one of the most prescribed medicines to improve lipid profiles. Statins include simvastatin, atorvastatin, and pravastatin. Many studies about the timing of statin intake to ensure higher efficacy. However, the investigations are short in duration (4-12 weeks,…
Heartburn is a prevalent complaint. It is the commonly used term for GERD or gastroesophageal reflux disease. The reflux is from the stomach acid going up in the chest due to the laxity of the esophageal sphincter. The esophagus has a delicate lining compared to the stomach, which makes it prone to reflux and acid…
The Previous article, The Circadian Rhythm: Timing is Everything, mentioned that peripheral clocks in all organs follow the master clock in the brain. This article is about the circadian rhythm of the cardiovascular system and when anti-hypertensives should be used to maximize their effect. The Cardiovascular System The cardiovascular system or CVS is made of the…
Circadian means “about a day” in Latin and has a 24-hour cycle. It is essential to know about circadian rhythms because there are times in a day when specific actions are optimal. An example is working during the day and resting during the night. If the activity and the circadian rhythm is out of timing,…
Four in 10 adults do not get enough sleep according to a 2014 Gallup poll. I suspect it is a lot more. Sleep deprivation can occur in three different ways. First is sleep fragmentation, where a continuous sleep is broken up. The second is ‘selective sleep restriction’ that occurs in obstructive sleep apnea. This results…
More patients with heart failure present to the emergency room during or after the holidays. This article aims to educate about the symptoms of heart failure and what to do to prevent it. Common Causes of Heart Failure Worsening Excessive salt intake Too much water intake Missed doses of medications or poor compliance Lung infections…
To control stress, it is vital to understand it. AnStress is not all bad. Stress is needed for survival. In daily life, fear makes us alert, meet deadlines, prepares us for a meeting, presentation, or a date, make us focus, and achieve our goals. In extreme situations, stress is needed for “fight or flight.” The…
It is a common belief that suicide rates are highest during the holiday season, but that is actually a myth, according to the Centers for Disease Control. The highest suicide rates happen during the spring and summer seasons. But why wait until someone is on the verge of harming themselves before something is done? We…
The Holiday Season is a time of fun and get-togethers. Food is always aplenty, and adding weight is a common concern. A study has shown that a weight gain of 0.48 kg (1 lb) can occur during the fall/winter period, and it can be more. Those added pounds can accumulate in a lifetime and lead…
Q: What do LeBron James, Jaromir Jagr, and Tom Brady have in common? A: They all have the most game-winning shots or drives in their respective leagues. Lebron James has the most Game-tying or go-ahead field goals with under 10 seconds left in the postseason. Jaromir Jagr has 135 game-winning goals, and Tom Brady holds…
Chewing preserves learning ability and spatial memory to maintain brain health and prevent dementia There is a special relationship between chewing and brain functions. As people grow older, memory loss can happen. This is not only due to the passage of time but is related to the loss of teeth and subsequent chewing dysfunction. To…
An object’s small cost does not negate its value. Every single item on this Christmas gift list are relevant to the subjects covered on this website. There is a list of recommended readings at the bottom. “As an Amazon Associate, I earn from qualifying purchases.” The list starts from the least to the most expensive….
Audio was added to this article on August 31, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. The use of light weights, resulting in the enlargement of skeletal muscle, was previously unheard of before KAATSU. It is the primary reason KAATSU is utilized in various fields, including…