Intermittent fasting Reverses Endothelial Dysfunction

This article presents three studies showing intermittent fasting could improve endothelial function. The endothelium is the inner lining of the blood vessels, and the cells in it do a full-time job of keeping it smooth, distensible, and open to maintain adequate organ perfusion, and lower blood pressure, resulting in less work for the heart. The…

After meal blood sugar spikes as a cause of vascular failure

This article is about the damaging effects of high blood sugar on the blood vessels after a meal. Post Prandial Hyperglycemia Post-prandial hyperglycemia (PPH) is the medical term for increased blood sugar after eating. It occurs if the blood sugar is 140 – 200 mg/dl two hours after eating. PPH can damage the arteries. The…

How to Prevent Hyperglycemia with the Vegetables-Meat-Carbs Sequence

This article presents a study that shows how to prevent the rapid rise of blood sugar after a meal or Post-Prandial Glycemia (PPG) After-Meal Blood Sugar and atherosclerosis High blood sugar after meals is a risk factor for developing diabetes and atherosclerosis. It injures the inner lining of the arteries and starts or continues atherosclerosis.[1]…

An Unusual Case of Parkinsonism Improvement After Nattokinase Use

This article was updated with English, Spanish and Mandarin audio on November 21, 2025 🎧 Introducción en audio — Español (Latinoamérica) En este audio comentaremos un caso clínico donde una persona con síntomas de parkinsonismo experimentó mejoría después de usar nattokinasa. Revisaremos qué ocurrió, cómo se interpretan estos hallazgos y por qué este tipo de…

Laboratory Studies on Nattokinase and Abnormal Protein Aggregates

Audio updated March 29, 2026, for Apple device compatibility. This article was updated with audio on August 15, 2025. This article discusses research showing that nattokinase can dissolve amyloid and prion proteins. What are Amyloids and Prions? Both are abnormal proteins because they are misfolded. Proteins in various parts of the body serve multiple functions….

Should You Take Nattokinase On An Empty Stomach?

Updated on November 25, 2025, with new English, Latin American Spanish, and Mandarin audio versions to help readers worldwide access this content and a brand new feature, the slideshow. 🎧 ▶️ Press the play button below to listen in English. 🇪🇸 Spanish (Latinoamérica) Hoy aprenderás si la nattokinasa debe tomarse en ayunas para una mejor…

Natto: An Application of the 80/20 Rule

This article was updated with audio on August 29, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. The 80/20 Rule The 80-20 rule, also known as the Pareto Principle, teaches us that a small effort often yields the majority of results. In health, this means just a few…

Nattokinase and Stroke Research: Understanding the Evidence

Updated on December 3, 2025, with new Latin American Spanish and Mandarin audio versions to help readers worldwide access this content. 🎧 ▶️ Press the play button below to listen in English.  🇪🇸 Spanish (Latinoamérica) En este audio descubrirás qué dice la evidencia más reciente sobre la nattokinasa y su posible papel en la prevención…

Insulin Resistance and Atherosclerosis and Nattokinase

This article was updated with Mandarin audio on November 20, 2025. Press play for the English audio below Your browser does not support the audio element. 🎧 Introducción en audio — Español (Latinoamérica) En este audio hablaremos de cómo la resistencia a la insulina contribuye al desarrollo de la aterosclerosis y por qué este proceso…

Soy Foods Do Not Increase Breast Cancer Risk

This article presents a series of studies showing that soy intake does not increase breast cancer risk. In contrast, the opposite is true. Soy intake lowers the risk of breast cancer. Breast cancer is currently the most common cancer globally, accounting for 12.5% of all new annual cancer cases worldwide. It is the second most…

High-Dose Nattokinase and Its Potential Benefits for Blood Vessel and Lipid Health

Update:This article has been revised and updated on November 21, 2025, to meet current E-E-A-T standards. The information has been reviewed for accuracy, clarity, and medical safety to ensure readers receive high-quality, evidence-based guidance. English audio below. Press play to listen 🎧 Audio Introduction — Mandarin (中文普通话) 在这段音频中,我们将介绍高剂量纳豆激酶,以及研究中观察到的它对血管健康和血脂水平的潜在益处。我们会说明主要发现、如何理解这些结果,以及需要注意的安全事项。本内容仅供教育参考,不能替代专业医疗建议。 Introduction Recent research suggests that higher doses…

Nattokinase is Nontoxic with a High Safety Margin

This article was updated with audio on November 20, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. 🎧 Introducción en audio — Español (Latinoamérica) En este audio veremos lo que dicen los estudios sobre la seguridad de la nattokinasa y por qué se considera un suplemento con…

Blood Glucose Spike and its Prevention

This article is based on an NHK Japan YouTube video about glucose spikes. A glucose spike or post-prandial hyperglycemia (PPG) is the rise of blood sugar to more than 140 mg/dL after a meal. It can happen after every meal. Many may unknowingly have glucose spikes, including those with normal fasting blood sugar and slender. In…

Prebiotics can bring out Reflux

Yesterday I wrote about my experience with gastroesophageal reflux disease (GERD) in The Post Holiday Heartburn. Further readings into the causes of GERD lead me to another reason many may not be aware of. One of my articles about COVID-19, Gut Microbiome Changes even in mild COVID-19 and what to do about it discussed that…

The Post Holiday Heartburn

I want to share with you my experience with the recent holiday celebrations. Years ago, I used to have frequent heartburns. Doctors call it gastroesophageal reflux disease or GERD. I used to take a lot of TUMS or Rolaids. Working in the emergency department, drinking coffee, and having a poor diet did not help either….

Gallbladder Diseases and Metabolic Syndrome

Audio was added to this article on August 31, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. First published on April 9, 2019. This page is updated with new information. Metabolic Syndrome is a common condition that increases the risk of coronary heart disease, obesity, and Type…

Inflammatory molecules found in Long COVID patients

A new study showed several inflammatory markers in the blood of patients with Long COVID. The inflammation leads to micro clots that are difficult to dissolve naturally. This leads to the extensive formation of clots. I think this will be the exact mechanism in people who develop blood clots after mRNA COVID vaccination since the…