mRNA COVID-19 Booster Shots Increase the Immunotolerant IgG4

This article features the findings of a new preprint study: Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming. It was published two days ago by BioRxiv. What is IgG4? Antibodies are one of the body’s first defenses against an…