A case series from Japan looked at how many people had a ruptured intracranial aneurysm after receiving the mRNA COVID shots.
A brain aneurysm is a ballooning of a blood vessel in the brain. Cerebral aneurysms tend to rupture and cause a subarachnoid hemorrhage (SAH).
Patients with a leaking brain aneurysm often say, “I have the worst headache in your life.” Once an emergency room doctor hears that phrase, they would rule out all the possible bad possibilities, including SAH.
A ruptured aneurysm is a surgical emergency due to its high fatality rate. Timely diagnosis is needed, and it can happen even to those in the 20s
The study reviewed the medical records of people who had a first and a second dose of an mRNA COVID shot between March 6, 2021, and June 14, 2021, in the Iwate district in Japan to see if anyone had a ruptured brain aneurysm.
Among 34,475 individuals vaccinated during the study period, they found three cases. All are women.
To know if the occurrence of the aneurysmal rupture differs from the normal incidence, they compared the incidence rate ratio of SAH with 5-year reference periods (2013-2017) also from March 6-June 14.
SAH after the COVID shot is 51 times more
They found that the incidence rate of ruptured cerebral aneurysms after mRNA COVID shots is 1058.7/100,000 person-years.
Another way to say that is if 100,000 people who had an mRNA shot were observed for one year, 1,058.7 will have a ruptured aneurysm within three days.
In comparison, only 83 had subarachnoid hemorrhage during the 5-year reference period for an incidence ratio of 20.7/100,000 persons-years.
The incidence of ruptured cerebral aneurysms among those who had the Pfizer shot is 51 times more than the reference period where no one got the shot.
All three cases developed SAH within three days (range, 0-3 days) of the first or second dose of the Pfizer BNT162b2 mRNA COVID-19 vaccine.
The median age at the SAH onset was 63.7 years (44- 75 years). Two had hypertension and dyslipidemia, and one had no medical problems. All survived after a timely microsurgical clipping or intra-aneurysm coiling.
In their discussion, the authors cited previous studies showing that women have a greater antibody response to immunizations [2], and the inflammatory response may have a role in the rupture of the aneurysms.[3]
Surgical Neurology International published the report in March 2022.
Comment:
A ruptured aneurysm is one cause of sudden death. The brain bleed can be massive such that one side of the brain will push against the breathing center, and the person will stop breathing. If the person is alone, death happens in minutes.
A brain aneurysm rupture can happen while driving, during sex, or early morning when the adrenaline rises.
There have been 196 subarachnoid hemorrhages reported in VAERS after the COVID jabs as of January 27, 2023. Some patients are too critical to undergo a prolonged imaging study to know what caused the SAH.
Take away message
A headache that is worse than usual needs immediate medical attention. Don’t wait for the next day. It may not come.
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Reference:
- Oshida S, Akamatsu Y, Matsumoto Y, Suzuki T, Sasaki T, Kondo Y, Fujiwara S, Kashimura H, Kubo Y, Ogasawara K. Intracranial aneurysm rupture within three days after receiving mRNA anti-COVID-19 vaccination: Three case reports. Surg Neurol Int. 2022 Mar 31;13:117. doi: 10.25259/SNI_1144_2021. PMID: 35509565; PMCID: PMC9062907.
- Resta C Di, Ferrari D, Viganò M, Moro M, Sabetta E, Minerva M, et al. The gender impact assessment among healthcare workers in the SARS-CoV-2 vaccination an analysis of serological response and side effects. Vaccines. 2021;9:522.
- Frösen J, Piippo A, Paetau A, Kangasniemi M, Niemela M, Hernesniemi J, et al. Remodeling of saccular cerebral artery aneurysm wall is associated with rupture: histological analysis of 24 unruptured and 42 ruptured cases. Stroke. 2004;35:2287–93
- United States Department of Health and Human Services (DHHS), Public Health Service (PHS), Centers for Disease Control (CDC) / Food and Drug Administration (FDA), Vaccine Adverse Event Reporting System (VAERS) 1990 – 01/27/2023, CDC WONDER On-line Database. Accessed at http://wonder.cdc.gov/vaers.html on Feb 3, 2023, 10:40:14 AM
- United States Department of Health and Human Services (DHHS), Public Health Service (PHS), Centers for Disease Control (CDC) / Food and Drug Administration (FDA), Vaccine Adverse Event Reporting System (VAERS) 1990 – 01/27/2023, CDC WONDER On-line Database. Accessed at http://wonder.cdc.gov/vaers.html on Feb 3, 2023, 12:34:12 PM
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