Coronary Stents, Blood Thinners and Disease Prevention
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Coronary Stents, Blood Thinners and Disease Prevention
🧠 Summary: Disease Prevention Is Better Than Stents and Blood Thinners
🚨 What Coronary Stents Are—and Why They’re Not a Cure
- A coronary stent is inserted into heart arteries to restore blood flow after a blockage.
- Although stents can prevent immediate heart damage, they are not a permanent fix.
- Stents are foreign objects; the body often tries to cover or block them with cells or clots.
- Even drug-eluting stents (DES) can still become blocked over time.
💉 Why Blood Thinners Are Required After Stenting
- After receiving a stent, patients are prescribed aspirin + another blood thinner (clopidogrel or ticagrelor) to prevent blood clots from forming inside the stent.
- According to AHA/ACC guidelines:
- Dual antiplatelet therapy (DAPT) is required for at least 12 months
- Aspirin must be taken for life
📊 Blood Thinner Risks in Numbers
| Combination | NNH (Number Needed to Harm) | Type of Harm |
|---|---|---|
| Aspirin + Clopidogrel | 1 in 114 | Major bleeding event |
| Aspirin + Ticagrelor | 1 in 166 | Major bleeding + breathlessness |
- These bleeding events often require hospitalization and blood transfusion.
- 1 in 16 patients on aspirin/ticagrelor also experienced shortness of breath.
- Independent analysis shows “no patients were helped” by aspirin/ticagrelor for certain outcomes—yet it remains recommended based on studies funded by the manufacturer.
🩺 The Cascade of Complications
- Stents can lead to reclogging, requiring more drugs to manage complications.
- Blood thinners increase bleeding risk and can delay or complicate elective surgeries.
- Emergency surgery decisions must weigh:
- Stop blood thinners → risk of heart attack
- Continue blood thinners → risk of surgical bleeding
💰 Cost of Medication
- As of 2019:
- Brilinta (ticagrelor): $379/month
- Plavix (clopidogrel): $11–$156/month
🧬 Statin Stats for Comparison
| Medication/Diet | NNT (Benefit) | NNH (Harm) |
|---|---|---|
| Mediterranean Diet | 1 in 18 helped | None harmed |
| Statins | 1 in 39 helped | 1 in 10 muscle damage, 1 in 50 diabetes |
✅ Disease Prevention Wins by a Long Shot
- Low-carbohydrate diets and intermittent fasting have nearly zero risk and profound benefits.
- Exercise, when done safely, carries almost no risk and protects against multiple chronic conditions.
- Both lifestyle strategies reduce:
- Heart attacks
- Metabolic syndrome
- Diabetes
- Obesity and related complications
🧠 Takeaway Message:
Don’t get sick
Medical interventions like stents and blood thinners are complex, costly, and risky.
The best way to avoid needing them is through simple, powerful prevention:
Eat better
Move more
🫀 Buod: Mas Mabisa ang Pag-iwas kaysa sa Stents at Blood Thinners
⚠️ Ano ang Coronary Stent at Bakit Hindi Ito Gamot
- Ang coronary stent ay isang maliit na tubo na inilalagay sa mga ugat ng puso para muling dumaloy ang dugo matapos ang bara.
- Nakakatulong ito na maiwasan ang pagkasira ng puso, pero hindi ito permanenteng solusyon.
- Dahil ang stent ay gawa ng tao, sinusubukan ng katawan na takpan ito gamit ang bagong mga selula—na maaaring magdulot ng panibagong bara.
- Kahit ang mga drug-eluting stents (DES) ay puwedeng bumara uli.
💊 Bakit Kailangang Uminom ng Blood Thinners Pagkatapos ng Stent
- Para maiwasan ang pamumuo ng dugo sa loob ng stent, kailangan uminom ng:
- Aspirin (81 mg araw-araw) at
- Isa pang blood thinner tulad ng clopidogrel (Plavix) o ticagrelor (Brilinta)
- Ayon sa American Heart Association:
- 12 buwan ang minimum na sabay na pag-inom ng dalawang gamot
- Habambuhay ang aspirin
📊 Mga Panganib ng Blood Thinners Ayon sa Datos
| Kombinasyon ng Gamot | NNH (Number Needed to Harm) | Anong Panganib? |
|---|---|---|
| Aspirin + Clopidogrel | 1 sa bawat 114 | Malalang pagdurugo (GI bleeding) |
| Aspirin + Ticagrelor | 1 sa bawat 166 | Pagdurugo + hirap sa paghinga |
- Ang mga pagdurugo ay madalas na nangangailangan ng pagka-ospital at dugo transfusion.
- 1 sa bawat 16 na pasyente sa aspirin/ticagrelor ang nagkaroon ng paghingal.
- Ayon sa independent review, ang kombinasyong ito ay walang naitulong sa pasyente — ngunit nire-rekomenda pa rin, base sa mga pag-aaral na pinondohan ng gumagawa ng gamot.
🧨 Kumplikasyon ng Sunod-sunod na Gamot
- Maaaring muling bumara ang stent → mas maraming gamot → mas maraming side effect
- Ang blood thinners ay:
- Nakakapagpahinto ng elective surgery
- Nagpapataas ng panganib sa internal bleeding
- Kung kailangan ng emergency surgery:
- Ititigil ba ang gamot at baka atakehin sa puso?
- O itutuloy ang surgery at baka magdugo nang malala?
💰 Presyo ng Gamot
- Presyo noong 2019:
- Brilinta (ticagrelor): $379/buwan
- Plavix (clopidogrel): $11–$156/buwan
🧮 Ibang Gamot at Diet Para sa Paghahambing
| Gamot/Diyeta | NNT (Benepisyo) | NNH (Pinsala) |
|---|---|---|
| Mediterranean Diet | 1 sa 18 nabiyayaan | Wala ni isang nasaktan |
| Statins | 1 sa 39 ang nabiyayaan | 1 sa 10 may muscle damage, 1 sa 50 nagka-diabetes |
✅ Panalo ang Pag-iwas sa Sakit
- Ang low-carb diet at intermittent fasting ay:
- Halos walang panganib
- May malawak na benepisyo
- Ang regular na ehersisyo ay ligtas kung ginagawa nang tama.
- Nakakaiwas hindi lang sa heart attack kundi pati sa:
- Metabolic syndrome
- Type 2 diabetes
- Altapresyon at labis na katabaan
🧠 Mensaheng Panghuli:
Ang paggamot ay magastos at puno ng komplikasyon.
Ang pag-iwas sa sakit gamit ang tamang pagkain at aktibong pamumuhay ay:
✅ Mas mura
✅ Mas ligtas
✅ Mas epektibo
Kumain ng tama. Gumalaw araw-araw. Huwag magkasakit.
Huwag Magkasakit! Don’t Get Sick!
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Related:
- The Deadliest Diseases Associated with Metabolic Syndrome
- Atrial Fibrillation and Metabolic Syndrome
- How Effective are Drugs that Increase HDL?
- Can You Be in Heart Failure Now?
- What Starts Atherosclerosis?
- The Magical Endothelium
- How Does Diabetes Destroy Arteries
- How Diabetes Destroys the Body
- Understanding Heart Failure Treatment
- How Effective is Quitting Cigarettes?
- Hair Loss and Heart Attacks
- The Real Effect of Statins on Heart Disease
- LDL: “Bad Cholesterol” is Not All Bad.
Image Credits:
Coronary Stent from the NIH
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