What type of COVID shot results in the most myocarditis? What are the age and sex affected?
These are the question answered by scientists from different institutions in the UK including Oxford University, King’s College London, and the British Heart Foundation Centre of Research Excellence. It was published yesterday as a preprint as Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
They analyzed a total of 42,200,614 people aged 13 years or more to see if there is an association between COVID-19 vaccination and myocarditis. The study stratified the results by age and sex and included 10,978,507 people receiving a third vaccine dose.
The associations for myocarditis and COVID shots were strongest in males younger than 40 years for all vaccine types.
Males <40 years old
For comparison, there is an excess of 7 cases of myocarditis in this age group after positive SARS-CoV-2 test per million population from the same study.[1]
The following results are expressed as excess cases per million population after vaccination for comparison.
Pfizer (BNT162b2)
- Three following the first dose
- 12 following the second dose
- 13 following the third dose
Moderna (mRNA 1273)
- 12 following the first dose
- 101 following the second dose
- None in the third dose; however, the number of vaccinees are small to make a meaningful conclusion
AstraZeneca ( ChAdOx1)
- One after the first dose
- 14 following the second dose
- none in the third dose (also small number of vaccinees)
Males >40 years old
- Three additional myocarditis events per million following the third dose of BNT162b2
- 73 after positive SARS-CoV-2 test. (No details regarding vaccination status)
Females <40 years old
- Eight events per million following the second dose of Moderna mRNA-1273
- Seven after a positive SARS-CoV-2 test.
Females >40 years old
There were no additional myocarditis events following any vaccination, but they have an additional 39 events per million following a positive SARS-CoV-2 test.
Take away message
The risk for myocarditis after the COVID shots are highest among males <40 years old, and the highest is after the second shot of Moderna. The risk of myocarditis increases with each succeeding dose of the Pfizer shot.
The authors conclude that getting myocarditis with COVID-19 is higher in the overall population than in COVID vaccinations.
We should put into context that the majority of the people who developed myocarditis after COVID-19 did not get the proper treatment that could have prevented COVID-19 myocarditis.
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Related:
- Circulation: Myocarditis related to COVID-19 shots in teenagers and young adults
- Anti-Idiotype Antibodies against the Spike Proteins may Explain Myocarditis
- mRNA Vaccination Increases the Risk of Acute Coronary Syndrome
- Kounis syndrome can explain vaccine-related heart attacks
- Myocarditis after mRNA Vaccination in the Military
- You Have to Know Vaccine Related Kounis Syndrome
- Myocarditis and the COVID vaccine
- This study shows Ten Fold risk of Developing Blood Clots after the COVID Vaccines.
- Platelet Changes Causes Blood Clots in COVID-19
- The High Risk of Deadly Brain Clots in the J & J COVID Vaccine
Reference:
Patone et al. Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
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