Nigella Sativa (NS), also known as Black Seed or Black Cumin, has been established to have antiviral, antibacterial, anti-inflammatory, and immunomodulatory
properties. The active ingredient in Nigella Sativa is thymoquinone (TQ). [1]
Studies have shown that NS is effective for early treatment of COVID-19, decreases hospitalization, and lowers mortality.
The website c19ns.com makes a meta-analysis of randomized-controlled trials about the use of NS in COVID-19.
Meta-analyses include the studies, the strength of the study, and the outcomes. The size of the diamond and squares reflect the number of people in the study. The more the figures go to your left, the greater the percentage of improvement.
The table below shows that early treatment with Nigella Sativa results in 84% improvement and 62% post-exposure prophylaxis (PEP).
The table below shows that NS. prevented hospitalization among 75% of people who had COVID-19.
Two studies with a total of 317 COVID-19 cases showed NS prevented death in 87% of the patients.
FLCCC Recommends Nigella Sativa
The FRONT LINE COVID-19 CRITICAL CARE ALLIANCE or FLCCC is a group of experienced clinicians in the US that treat COVID-19. They publish protocols for the prevention and treatment of COVID-19.
Nigella Sativa is recommended at 40 mg/kg a day in their prevention protocol. FLCCC recommends NS should be used if ivermectin is not available or added to ivermectin for optimal prevention. You can click on the links to print the protocols.
For early treatment of the Delta variant, the dose is higher at 80 mg/kg a day for 14 days. See the red arrow below.
Safety of Nigella Sativa
A meta-analysis demonstrated the beneficial effects of N. Sativa on fasting glucose, HbA1c, triglycerides, total-, VLDL-, LDL-cholesterol levels. [3]
A review of the literature showed that NS could lower alkaline phosphatase (ALP) and blood urea nitrogen (BUN). That is good. A daily dose of 1100-1500 mg of NS supplements was observed to reduce ALP levels and BUN. However, a dose of more than 2000 mg per day led to a significant increase in BUN concentrations. [5].
Note: A 70 kg individual who will take NS at 40 mg/kg will have 2,800 mg daily. A dose of 80mg/kg a day in the same 70 kg person will deliver 5600 mg a day.
Talk to your physician or consult a pharmacist before taking any nutritional supplements to know about possible drug interactions and if they are right for you.
Where to get Nigella Sativa or Black Seed Oil
These Black Seed Oil Capsules by Healths Harmony have the highest number of reviews and ratings on Amazon.
A liquid form is also available, Black Seed Oil – 3 Times Thymoquinone, Cold-Pressed, 100% Turkish Black Cumin Seed Oil, Liquid Pure Blackseed Oil, Glass Bottle, 8 oz
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References:
- Koshak AE, Koshak EA, Mobeireek AF, et al. Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial. Complement Ther Med. 2021;61:102769. doi:10.1016/j.ctim.2021.102769
- c19ns.com
- FLCCC Protocols
- Hallajzadeh J, Milajerdi A, Mobini M, Amirani E, Azizi S, Nikkhah E, Bahadori B, Sheikhsoleimani R, Mirhashemi SM. Effects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of beneficial effects of N. Sativa on fasting glucose, HbA1c, triglycerides, total-, VLDL-, LDL-cholesterol levels. inflammatory and oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trials. Phytother Res. 2020 Oct;34(10):2586-2608. doi: 10.1002/ptr.6708. Epub 2020 May 11. PMID: 32394508.
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Razmpoosh E., Safi S., Abdollahi N. The effect of Nigella sativa on the measures of liver and kidney parameters: a systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2020;156:104767. doi: 10.1016/j.phrs.2020.104767.
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