Pfizer Lot Numbers with the Most Reported Deaths Examined

Part 1 of the Vaccine Lot Numbers Examined

This is a brand-new article listing the top 100 Pfizer COVID-19 vaccine lot numbers, using the latest CDC Wonder data from the rollout year, 2021, through April 24, 2026.

🎧 ▶️ Press the play button below to listen.

Introduction

This article is in response to the interest given to an old article. Pfizer COVID-19 Vaccine Lot Numbers with the Most Deaths. The data here is current as of April 2026.

They are drawn directly from the U.S. Vaccine Adverse Event Reporting System (VAERS) — a national passive surveillance database co-managed by the CDC and FDA.

VAERS accepts reports from healthcare providers, vaccine manufacturers, and the public. Anyone can submit a report, and they are encouraged to report any clinically significant health problem following vaccination, whether or not they believe the vaccine caused it.

Because of this, VAERS data alone cannot tell us whether a vaccine caused a death. The reports may be incomplete, inaccurate, coincidental, or unverifiable. They also lack a denominator — meaning we do not know how many doses of each lot were given.

However, there is another critical factor that readers must understand: the opposite problem of underreporting.

The Other Side: VAERS Dramatically Underreports Adverse Events

While VAERS data has limitations, experts also acknowledge that the system captures only a tiny fraction of actual adverse events. The Lazarus Report — a grant final report submitted to the U.S. Department of Health and Human Services (AHRQ Grant No. R18HS017045) — investigated adverse event reporting by comparing electronic medical records to VAERS records. Their findings were striking:

“Although 25% of ambulatory patients experience an adverse drug event, less than 0.3% of all adverse drug events and 1-13% of serious events are reported to the Food and Drug Administration (FDA). Likewise, fewer than 1% of vaccine adverse events are reported.”

This means that for every vaccine adverse event that occurs, fewer than 1 in 100 is ever reported to VAERS. For COVID-19 vaccines specifically, some researchers have found that underreporting may be even more pronounced because vaccines were administered at non-traditional sites (pharmacies, pop-up clinics, mass vaccination sites) where adverse event reporting was less systematic than in traditional healthcare settings.

What This Means for Interpreting the Data

These two realities exist simultaneously:

VAERS has false signals	AND	VAERS misses most true events
Coincidental deaths are reported		Fewer than 1% of adverse events are reported
Reports may be incomplete or inaccurate		COVID-19 vaccine reporting may be even worse
No causation can be determined from VAERS alone		The true number of adverse events is almost certainly much higher

Therefore, the raw numbers in the table below — while useful for identifying potential safety signals — almost certainly represent a small fraction of actual adverse events that occurred. The true number of deaths following vaccination is unknown, but experts agree it is significantly higher than what VAERS captures.

With those critical limitations in mind, the table below shows the Pfizer COVID-19 vaccine lot numbers with the highest number of death reports in VAERS, updated through April 2026. These numbers are raw counts, not rates, and should not be interpreted as evidence that any lot was unsafe.

Additional Complexity: Booster Shots and Mixed Vaccine Series

There are two additional factors that make interpreting VAERS data — and assigning adverse events to a specific lot or vaccine — extremely difficult, especially for later years.

1. If an adverse event occurs after a booster, was it caused by the booster or the original shot?

This is a critical question that VAERS cannot answer.

Consider a person who:

• Received their primary Pfizer series in early 2021 (Lot A and Lot B)
• Received one or more Pfizer boosters in 2022, 2023, or 2024 (Lot C, Lot D, etc.)

If that person experiences a serious adverse event (e.g., myocarditis, stroke, autoimmune condition) in 2024 — weeks, months, or even years after their last booster — the VAERS report will typically list only the most recent vaccine lot (the booster) as the suspect product. However, the adverse event could theoretically be related to:

• The booster itself (Lot C or D)
• The original primary series (Lot A or B), with delayed onset
• An interaction between doses
• Purely coincidental background illness

VAERS cannot distinguish between these possibilities. The database does not track individual vaccination histories in a way that allows researchers to link an adverse event to a specific dose from years earlier. Therefore, adverse events reported after booster doses cannot be reliably attributed to the booster versus the original shots.

2. Mixing vaccines within a series further confounds the problem

Millions of Americans received:

• Pfizer for dose 1, Moderna for dose 2 (or vice versa)
• Pfizer or Moderna for the primary series, then a Novavax or J&J booster
• Different brands across multiple boosters

In these cases, if an adverse event occurs, VAERS typically records only the vaccine given at the most recent dose (or the one the reporter believes caused the event). The contribution of prior doses from other manufacturers is lost.

Scenario	What VAERS Records	What VAERS Cannot Tell You
Pfizer primary series (2021), Pfizer booster (2023), adverse event (2024)	Booster lot number	Whether the original 2021 doses contributed
Pfizer dose 1, Moderna dose 2, adverse event after dose 2	Moderna lot number	Whether Pfizer dose 1 played a role
Three different boosters over two years	Only the last lot (if any)	Which dose (or combination) caused the event

This mixing means that even if a later-year adverse event is correctly reported, the lot number in VAERS may not represent the true cause — or even the only relevant vaccine.

What This Means for Interpreting Later-Year Data

If you see…	You cannot conclude…
A 2023 or 2024 lot with death reports	That the booster caused the deaths
No reports for a 2023 lot	That the booster is safer (it may be underreported or administered to healthier people)
A report blaming a specific lot	That lot is definitely the cause (prior doses may be responsible)
A report after mixed vaccination	Which brand or lot caused the event

---

Summary of Key Caveats

What these numbers ARE	What these numbers ARE NOT
Reports of death after vaccination	Proof of death because of vaccination
Useful for generating hypotheses	Useful for determining safety or risk
A reflection of reported volume	A reflection of actual death rates
Known to capture fewer than 1% of events	A complete or accurate count
Able to record only the most recent vaccine lot	Able to identify which dose in a series caused an event

---

First, the Raw Numbers (from CDC WONDER)

The table below shows Pfizer lots with the highest number of death reports in VAERS as of April 2026. These are real reports submitted by healthcare providers, family members, or the public.

Top 50 Pfizer COVID-19 Vaccine Lots by VAERS Death Reports

Rank	Vaccine Lot	Total Death Reports (All Months Combined)
1	EN6201	236
2	EN6200	182
3	EN5318	179
4	EN6198	177
5	EL9269	176
6	EN6202	168
7	EN6207	162
8	EN6205	162
9	EN6204	150
10	EM9810	142
11	EN6208	128
12	EN6203	120
13	EL9261	113
14	EL9267	109
15	EN6206	95
16	EL3248	94
17	EL3249	93
18	EL0140	90
19	EL9265	89
20	EL3302	88
21	EL9262	86
22	EL8982	84
23	EN9581	83
24	EL9264	82
25	EL9266	80
26	EP6955	74
27	EL1283	73
28	EP7534	72
29	ER8727	71
30	EL0142	68
31	EJ1686	67
32	EK9231	66
33	EL1284	63
34	EM9809	62
35	ER8730	58
36	EL3246	56
37	EK4176	53
38	ER8737	52
39	ER8732	49
40	EW0171	48
41	EW0150	47
42	ER8731	47
43	ER8733	46
44	EJ1685	45
45	EW0162	45
46	EL3247	44
47	EW0151	43
48	EM9808	43
49	ER8734	43
50	EW0169	42

Ranks 51–100

Rank	Vaccine Lot	Total Death Reports
51	EW0153	41
52	EW0161	41
53	EW0172	40
54	EW0175	40
55	ER8735	39
56	EW0164	39
57	EN6199	38
58	EP7533	38
59	EW0158	38
60	EW0179	38
61	EL9263	37
62	EW0167	37
63	EW0170	37
64	EK5730	36
65	EW0168	36
66	EW0177	35
67	EW0182	35
68	ER8736	34
69	EW0176	34
70	EW0185	34
71	FC3184	33
72	EH9899	32
73	EW0180	32
74	EW0186	32
75	EM9808	31
76	EW0181	31
77	EW0187	31
78	EW0191	31
79	ER2613	30
80	EW0165	30
81	FC3182	30
82	EW0178	29
83	EW0196	29
84	FC3183	29
85	EL9261 (duplicate variant?)	28*
86	FC3180	28
87	FD0810	28
88	EW0183	27
89	FF2593	27
90	EM9809	26
91	EW0160	26
92	FC3181	26
93	ER8729	25
94	EW0173	25
95	FF2588	25
96	FD0809	24
97	FF2587	24
98	FF2589	24
99	FH8028	24
100	FH8030	24

The top 100 lot numbers listed here are from the original monovalent Pfizer vaccine given in 2020–2021.

Later booster formulations (bivalent, XBB, JN.1) are recorded under different VAERS product codes and are not included in this ranking. They will be the subject of a future article in this series.

Comparing raw death counts between original shots and boosters would be invalid — not only because of different populations, but because they are different vaccines in the VAERS database.

Important Notes on These Numbers

1. These are raw, unverified VAERS reports — not proven vaccine-caused deaths.
2. No denominator — we do not know how many doses of each lot were administered.
3. Top lots are almost entirely from Dec 2020 – May 2021, when vaccination targeted the oldest, sickest populations and reporting was most intense.

The Critical Caveat You Won’t See in a Screenshot

VAERS is a passive surveillance system. Anyone can submit a report. The criteria are intentionally broad: healthcare providers are encouraged to report any clinically significant health problem following vaccination, whether or not they believe the vaccine caused it.

The CDC and FDA are very clear:

“VAERS reports alone cannot be used to determine if a vaccine caused or contributed to an adverse event or illness. The reports may contain information that is incomplete, inaccurate, coincidental, or unverifiable.”

In other words:
A death report in VAERS means a death occurred after vaccination, not because of it.

Why High-Report Lots Are Not “Dangerous”

1. High-volume lots produce more reports by chance

Early Pfizer lots (late 2020 through early 2021) were distributed to millions of people, especially the elderly in nursing homes and long-term care facilities. If you give 2 million doses of a single lot to a population where 0.5% would die from any cause within a few weeks, you will see thousands of background deaths — all of which may be reported to VAERS.

2. No denominator = no rate

VAERS does not tell you how many doses of each lot were given. A lot with 100 reports and 10 million doses is far safer than a lot with 10 reports and 10,000 doses. Without that denominator, raw counts are meaningless for comparing safety.

3. Reporting bias is extreme

Early in the pandemic, any death after vaccination was headline news. Doctors, families, and even coroners were more likely to file a VAERS report. Later, lots received far less scrutiny, so underreporting increased. This skews the data dramatically toward early 2021.

4. Coincidental deaths are expected

Even with a perfectly safe vaccine, a certain number of deaths will occur by chance in the days or weeks following vaccination — due to heart attacks, strokes, cancer, infections, accidents, or COVID itself. VAERS captures those, but cannot distinguish them from true vaccine reactions without further investigation.

What Happens When CDC Actually Investigates

When VAERS detects a “safety signal” (e.g., a lot with many reports), the CDC and FDA do not stop there. They use more rigorous systems like:

• Vaccine Safety Datalink (VSD) – active surveillance with medical records and control groups
• Clinical Immunization Safety Assessment (CISA) – in-depth case reviews

To date, no Pfizer lot has been withdrawn or flagged as unsafe based on VAERS data. In every case where a lot appeared to have high death reports, follow-up studies found no causal link. The reports were either coincidental or reflected high vaccine use in vulnerable populations.

Take Aways

If you see…	Do not conclude…	Instead understand…
A lot with 100+ death reports	The lot is dangerous	The lot was likely used widely in early 2021
A lot with zero death reports	The lot is safer	The lot may have been used less, or later, or underreported
Rising death reports over time	Safety is getting worse	Reporting intensity and vaccine distribution changed

The Bottom Line

The COVID-19 pandemic has taught us many lessons — not all of them coming from mainstream medicine. Patients, families, independent researchers, and community doctors also observed, documented, and asked hard questions. Some of those questions have not yet been fully answered.

VAERS is one tool among many. It is flawed, incomplete, and easily misunderstood. But it is also one of the few windows the public has into what is being reported — and what is not.

Whether you are a vaccine advocate, a skeptic, or somewhere in between, the data in this article should not be used to declare any lot “safe” or “dangerous.” Instead, it should remind us of something broader:

People should look back and learn from what happened — because it can possibly happen again.

Another pandemic. Another vaccine. Another rapid rollout. Another passive surveillance system with the same strengths and the same weaknesses.

The question is not whether VAERS is perfect or worthless. The question is whether we — as individuals, as communities, and as a country — will remember what we learned this time. Will we demand better reporting systems? Will we track lot-specific outcomes with denominators? Will we honestly investigate both underreporting and coincidental reports?

Those lessons are not in any lot number. They are in how we choose to respond now.

Don’t Get Sick!

About Dr. Jesse Santiano, MD

Dr. Santiano is a retired internist and emergency physician with extensive clinical experience in metabolic health, cardiovascular prevention, and lifestyle medicine. He reviews all medical content on this site to ensure accuracy, clarity, and safe application for readers. This article is for educational purposes and is not a substitute for personal medical care.

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Related:

1. Pfizer COVID-19 Vaccine Lot Numbers with the Most Deaths
2. Lot Numbers of Pfizer and Moderna mRNA Vaccines with the Highest Deaths
3. Moderna COVID-19 Vaccine Lot Numbers with the Most Deaths: Medalerts
4. Pfizer and Moderna shots increase all cause mortality: Denmark study
5. Blood Vessel Damaging Proteins of the SARS-CoV-2
6. Cerebral Thrombosis after the Pfizer Covid-19 Vaccine
7. The High Risk of Deadly Brain Clots in the J & J COVID Vaccine
8. This Study shows a Ten Fold Risk of Developing Blood Clots after the COVID Vaccines.
9. You got the COVID shot and found that others developed blood clots. Now what?
10. Platelet Changes Causes Blood Clots in COVID-19
11. Unidentified Foreign Bodies in the Vaccines Form Clots

References:

• United States Department of Health and Human Services (DHHS), Public Health Service (PHS), Centers for Disease Control (CDC) / Food and Drug Administration (FDA), Vaccine Adverse Event Reporting System (VAERS) 1990 – 04/24/2026, CDC WONDER On-line Database. Accessed at http://wonder.cdc.gov/vaers.html on May 16, 2026 8:56:36 PM
• Lazarus, R. (2010). Electronic Support for Public Health – Vaccine Adverse Event Reporting System (ESP: VAERS) – Final Report (Grant No. R18 HS017045). Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services.

Disclaimer:
This article is for educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician before making health decisions based on the TyG Index or other biomarkers.

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