Tag: caloric restriction

A high fat diet may lead to inflammation and colorectal cancer

Posted on by Jesse Santiano, M.D.

A study published in Cell Research in July 2022 shows that a high-fat diet can lead to inflammation and possibly colorectal cancer. The study by Deng et al. showed that a high-fat diet increases the leptin receptors and insulin-like growth factor 1 (IGF1) in the intestinal stem cells (ISC).[1] Leptin is a hormone that regulates…

Caloric restriction mimics the positive effects of beta-blockers on the heart

Posted on by Jesse Santiano, M.D.

This article features a study that showed that caloric restriction has the same benefits that beta-blockers provide to failing hearts. Beta-blockers like metoprolol and atenolol are recommended for people with congestive heart failure (CHF). Failing hearts cannot supply enough blood. That is why people with CHF constantly feel weak and short of breath. In heart…