Tag: glibenclamide

Intermittent Fasting vs Diabetes Drugs: Sulfonylureas

Posted on by Jesse Santiano, M.D.

What is Sulfonulyrea? Sulfonylureas are prescribed for Type 2 diabetes. The common ones are glyburide, glibenclamide, glipizide, and glimepiride. How Do Sulfonylureas Work? Sulfonylureas work by making the beta cells of the pancreas release more insulin. Why Do You Need Sulfonylureas for that? Isn’t Insulin Release Normal and Automatic? Usually, when the body senses a…

Prescriptions that Promote and Pharmaceuticals that Prevent Ischemic Preconditioning

Posted on by Jesse Santiano, M.D.

Take Away Message: Commonly used prescription medicines like the diabetic drug family of sulfonylureas like glyburide and glibenclamide, the asthma drug aminophylline, and the opioid reversal agent naloxone can worsen the outcome of a heart attack or stroke by interfering with ischemic preconditioning. Review of Ischemic Preconditioning (IPC) What is Ischemic Preconditioning? is an introduction to the subject of IPC….