Four Ways Antibodies are Transferred from the COVID Jabbed to the Unvaxxed: Big Deal?

This article presents studies showing four ways that antibodies from those vaccinated against COVID-19 can be transferred to others, including the unvaxxed. But is it a cause for concern?

Let’s look at the research papers showing the transmission of anti-SARS-CoV-2 antibodies first.

1. Aerosol and Droplet Transmission

A study published by the official journal of the American Association of Immunologists, ImmunoHorizons, this May 2023, showed droplet and aerosol transmission of anti-spike protein antibodies from the vaccinated.[1]

The research Evidence for Aerosol Transfer of SARS-CoV-2–Specific Humoral Immunity studied saliva and mask samples from laboratory workers all day and found IgG and IgA antibodies against SARS-CoV-2.

Immunoglobulin A or IgA are antibodies that are present in the lining of the nose and the mouth. IgGs are antibodies that are circulating in the blood. Some IgGs are multipurpose and can take care of any germs. While other IgGs are specialized and produced in response to a specific bacteria or virus.

Proof of Transfer

To add evidence to their conclusion that anti-SARS-CoV-2 antibodies can be transmitted to the unvaxxed, they took samples from unvaccinated and COVID-negative children living in households in which parents or family members had varying degrees of SARS-CoV-2–specific immunity, including those unvaccinated, vaccinated, and COVID-19 positive.[1]

Their hypotheses will be considered wrong if the children living with the vaccinated will have no anti-spike protein antibodies. Note: The mRNA shots will only induce anti-spike antibodies because they do not have the nucleocapsid mRNA.

But they were right. They found that children living with others who are vaccinated have antibody levels that parallel the number of spike antibodies their other household members have.

The image below shows the IgG antibody levels from the nose of the vaccinated adults and their children. High levels are in gray, and low is in green. Notice that the levels of IgGs in unvaccinated children track the levels in vaccinated adults.

In contrast, both unvaccinated adults and their children have undetectable anti-spike IgGs.

Source: Evidence for Aerosol Transfer of SARS-CoV-2–Specific Humoral Immunity. *Immunohorizons* 1 May 2023; 7 (5): 307–309.

2. Platelet Transfusion

The journal Transfusion published Passive Transfer of SARS-CoV-2 antibodies with platelet Transfusions in April 2022.

The study found that 13 out of 23 patients, or 56%, who previously had no antibodies against the spike proteins became positive for SARS-CoV-2 spike protein antibodies. [2]

According to the US National Blood Collection and Utilization Survey in 2017, over 1.937 million platelet transfusions were given, or approximately 5300 units per day[4]

3. Mother to Fetus or Placental Transfer

In a study of 1471 mother-newborn pair from the Pennsylvania Hospital, IgGs against the SARS-CoV-2 from mothers who had asymptomatic and symptomatic infections were transferred to their babies.

The Journal of the American Medical Association Pediatrics published Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios in June 2021.[4]

4. Breast Milk

As early as February 2022, evidence has shown that COVID-vaccinated mothers have neutralizing antibodies against the SARS-CoV-2. The results were published in Neutralizing Antibodies and Cytokines in Breast Milk After Coronavirus Disease 2019 (COVID-19) mRNA Vaccination [5]

In another study, Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure.

They found higher IgG and IgA levels in lactating mothers who received mRNA-based vaccines (Pfizer and Moderna) compared to AstraZeneca and those with previous virus exposure.

Not only newborns but sexual partners could also be exposed to spike antibodies from breast milk and saliva.

Knowing the mechanisms of transfer of antibodies, is it a cause for concern? First, let’s differentiate between active and passive immunity.

Active and Passive Immunity

Active immunity occurs when the body produces antibodies in response to prior infections or vaccinations like the MMR, Polio, TB, and Tetanus toxoid vaccines, and many others.

Antibodies from active immunity are made by the B cells that have the memory of the antigen.

Passive Immunity is when ready-to-use antibodies are transferred to another person. The B cells are not involved, and the body will not produce the passive antibodies it was exposed to, whether inhaled, ingested, transfused, or transferred through the placenta.

In a few days or weeks, the recipient’s immune system treats the transferred antibodies as another foreign protein and gets rid of it.

Do passive antibodies provide protection?

They do. That is why mothers were encouraged to breastfeed their babies decades before the pandemic started. The colostrum, or the milk produced after the baby’s delivery, is rich in antibodies and protects the newborn while it develops its immunity.

Passive immunity is also the principle behind convalescent plasma transfusion from those who survived the SARS-CoV-2 to those with severe COVID-19.

There is no research yet about the effectiveness of inhaled COVID antibodies.

Possible Reactions to Passive Antibodies

Naked monoclonal antibodies are used for cancer treatment. They are injected in the vein and could potentially lead to:

Rashes
Fever
Chills
Weakness
Headache
Nausea
Vomiting
Diarrhea
Low blood pressure

Low blood pressure is the worst, but the reactions typically depend on the dose. So, platelet transfusion has the worst potential among the four ways of passive anti-spike antibody transfer.

Transmitted antibodies from the COVID vaccine will not cause the same side effects as the mRNA shots, and because of that, the vaccinated and the unvaxxed can continue to work, live, and love each other.

Truth heals. Lies kill. Don’t Get Sick!

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Related:

After writing this, I found out I wrote about the featured research back in May 2022 when the paper was still a preprint. Study shows the aerosol transfer of vaccine-induced COVID antibodies to the unvaxxed

References:

Ross M. Kedl, Elena W. Y. Hsieh, Thomas E. Morrison, Gabriela Samayoa-Reyes, Siobhan Flaherty, Conner L. Jackson, Rosemary Rochford; Evidence for Aerosol Transfer of SARS-CoV-2–Specific Humoral Immunity. Immunohorizons 1 May 2023; 7 (5): 307–309.
Ramirez GA, Gautam-Goyal P, Shariatmadar S, Khatri A, McCann-Pineo M, Rasul R, Karkenny G, Chang T, Sfakianos M, Cassiere H, Epstein M. Passive transfer of SARS-CoV-2 antibodies with platelet transfusions. Transfusion. 2022 Apr;62(4):764-769. doi: 10.1111/trf.16841. Epub 2022 Feb 26. PMID: 35191047; PMCID: PMC9115505.
Jones JM, Sapiano MR, Savinkina AA, Haass KA, Baker ML, Henry RA, et al. Slowing decline in blood collection and transfusion in the United States – 2017. Transfusion. 2020;60(S2):S1–9.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Bolton MJ, Arevalo CP, Anderson EM, Goodwin EC, Hensley SE, Puopolo KM. Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. 2021 Jun 1;175(6):594-600. doi: 10.1001/jamapediatrics.2021.0038. PMID: 33512440; PMCID: PMC7846944.
Narayanaswamy V, Pentecost BT, Schoen CN, Alfandari D, Schneider SS, Baker R, Arcaro KF. Neutralizing Antibodies and Cytokines in Breast Milk After Coronavirus Disease 2019 (COVID-19) mRNA Vaccination. Obstet Gynecol. 2022 Feb 1;139(2):181-191. doi: 10.1097/AOG.0000000000004661. PMID: 35104067; PMCID: PMC8759542.
Selma-Royo M, Bäuerl C, Mena-Tudela D, Aguilar-Camprubí L, Pérez-Cano FJ, Parra-Llorca A, Lerin C, Martínez-Costa C, Collado MC. Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study. Genome Med. 2022 Apr 21;14(1):42. doi: 10.1186/s13073-022-01043-9. PMID: 35449030; PMCID: PMC9022055.
Monoclonal antibodies and their side effects

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