This article is about the efficacy of Cetylpyridinium chloride (CPC) in killing SARS-CoV-2 viruses.
The research, Virucidal activity, and mechanism of action of cetylpyridinium chloride against SARS-CoV-2 is from The University of Miyazaki in Japan and is a preprint at medRxiv.
The authors tested the antiviral activity of cetylpyridinium chloride or CPC against SARS-CoV-2. CPC is an ingredient in mouthwashes like Crest Pro-Health Intense Mouthwash (0.05% CPC), Colgate Total Pro-Shield Alcohol-Free Mouthwash (0.075% CPC), and TheraBreath Healthy Gums (0.05% CPC).
As an Amazon Associate, I earn from qualifying purchases
Their study showed the CPC concentrations at (0.05%, 0.1%, and 0.3%) effectively inactivated SARS-CoV-2 within 20 and 60 seconds.
The table below shows their results. At 0.05% CPC concentration, 91.9 % of the viruses were reduced at 20 seconds contact time, and at 60 seconds, >97% of the viruses were reduced. The CPC’s disrupts the viral envelope and inactivates the viral enveloped SARS-CoV-2.
Povidone-Iodine (PI) was used as a positive control. You can see on the table that it is also effective as a mouthwash to prevent upper respiratory tract infections. Nasal rinse and deep gargle stop viral respiratory infections in their tracks.
Okamoto and colleagues also showed that CPC prevented the spike protein of the SARS-CoV-2 from adhering to the ACE2 receptors by denaturing the spike protein rendering it ineffective for ACE2 attachment.
Figure A below shows the lower reduction of spike-ACE2 binding at 0.05% concentration. Figure B shows the highest reduction in binding with the 0.05% concentration compared to 0%, 0.0125%, and 0.3%.
The study adds that CPC mouthwashes and povidone-iodine mouthwashes can stop COVID-19 infections before they worsen. Initial viral loads determine COVID-19 severity.
Mouthwashes are readily available and inexpensive ways to avoid an expensive hospital bill.
Don’t Get Sick!
Knowledge about Covid-19 is rapidly evolving. Stay current by subscribing. Feel free to share and like.
If you find value in the articles, please consider donating to show your support.
Related:
- Update to FLCCC Treatment Protocol for the Delta Variant
- COVID-19 Symptoms in the Vaccinated and Unvaccinated
- Update to the I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19
- What should the household do if someone has an Early COVID-19?
- The I-MASK+ for the Prophylaxis and Early Treatment Protocol of COVID-19
- The MATH+ Protocol Results in Greater Survival in Hospitalized COVID-19 Patients
- The I-RECOVER Management Protocol for Long Haul COVID-19 Syndrome
- Melatonin’s Multiple Actions Against COVID-19
- Nasal Povidone-Iodine Works Great for the Prevention and Early Treatment of COVID-19!
- Vitamin C and COVID-19
- Zinc Deficiency Impairs the Immune System
- Adequate Vitamin D Prevents Severe COVID-19
Reference: