This article is unique because it is about a man whose Hodgkin’s lymphoma disappeared after he had COVID-19.
Hodgkin’s lymphoma is a cancer of the lymphocytes. A common sign is enlarged lymph nodes all over the body.
Case Report
The patient is a 61-year-old patient receiving hemodialysis for end-stage renal failure. Before getting sick with COVID-19, he was diagnosed with Epstein–Barr virus (EBV)-positive classical Stage III Hodgkin lymphoma with an EBV viral polymerase chain reaction (PCR) of 4800 copies/ml; log10 3·68.
A PET scan confirmed the spread of the lymphoma. (see below)
After his lymphoma diagnosis, he was admitted to the hospital for breathlessness and wheezing and he tested positive for SARS-CoV-2 pneumonia.
After 11 days of supportive care for COVID-19 without corticosteroid or immunochemotherapy, he was discharged to recover at home.
Remission
Four months later, the enlarged and palpable lymph nodes became smaller. A PET/CT scan revealed widespread resolution of the lymphadenopathy and reduced metabolic uptake throughout.
The image below on your left was the PET scan when he had Hodgkin’s lymphoma. The right image shows the remission of the lymphoma.
The EBV viral PCR had also fallen to 413 copies/ml (log10 2·62).
Challenor and Tucker, the case report’s authors, hypothesized that the immune response triggered by the SARS-CoV-2 was also responsible for the remission of Hodgkin’s lymphoma.
This is interesting since recently, I wrote The Carcinogenic Effects of the SARS-CoV-2, where I discussed potential cancer-causing effects of the SARS-CoV-2.
So it seems like the COVID-19 virus has both pro and anti-cancer effects.
My other article, Dietary changes to remove the Warburg Effect and prevent cancer, discusses how to reduce the carcinogenic effect of COVID-19.
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Reference:
Challenor S, Tucker D. SARS-CoV-2-induced remission of Hodgkin lymphoma. Br J Haematol. 2021 Feb;192(3):415. doi: 10.1111/bjh.17116. Epub 2021 Jan 2. PMID: 33386647.
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