Clinical Outcomes of Omicron subvariants including XBB, the dominant SARS-CoV-2 in the US

The Omicron subvariant XBB.1.5 is the dominant cause of COVID-19 in the US. It is highly infectious and resistant to previous vaccinations, therapeutic monoclonal antibodies, and immunity from past infections. Being highly infectious is concerning, but does it have a high fatality rate? That is what is more important. Today, a new study was released…

The Dominant Omicron XBB1.5 Evades Antibodies and has Stronger ACE2 Binding

The XBB 5.1 is the most dominant SARS-CoV-2 Omicron subvariant in the US. According to the latest CDC COVID Data Tracker as of Dec 31, 2022, it causes 41% of COVID-19.[1] Origin of the XBB A study from Japan traced the origin of the XBB subvariant. It emerged after two co-circulating BA.2 lineages, BJ.1 and…

Breakthrough infection provides greater protection than a booster shot

This article talks about a new preprint study from Oxford University showing that a COVID-19 breakthrough infection provides better and longer protection than a booster shot. A breakthrough infection is a COVID-19 infection in those with COVID-19 jabs. In the investigation, the authors compared whether a third or booster shot or a breakthrough infection following…

The problems with Omicron-booster shots

This article talks about the reasons why Dr. Paul Offit voted against the approval of the booster shots designed for the Omicron variant. Dr. Paul Offit is a member of the Vaccines and Related Biological Products Advisory Committee (VRBPAC), which advises the FDA on whether new vaccines should be approved. VRBPAC met on June 28…