Tag: nirmatrelvir

13 Reasons Why COVID-19 Cases and Deaths May Increase Again

Posted on by Jesse Santiano, M.D.

Update Jan 12, 2023: I added another reason. SARS-CoV-2 variants of concern developed resistance to interferon as the pandemic progressed. Much new information came out recently about SARS-CoV-2, which causes COVID-19, the antivirals prescribed for it, and its “vaccines.” This article aims to increase awareness that SARS-CoV-2 reinfections can happen no matter if they have…

Paxlovid blunts adaptive immune response to SARS-CoV-2

Posted on by Jesse Santiano, M.D.

This article highlights a new study showing that Nirmatrelvil, the active ingredient in Paxlovid, prevents an adequate adaptive immune response to the SARS-CoV-2 virus. In the study, the SARS-CoV-2-infected mice failed to develop antibodies, memory T cells, and B cells specific to SARS-CoV-2 on initial and second exposure to the virus. The K18-hACE2 mice used…