mRNA COVID-19 Booster Shots Increase the Immunotolerant IgG4

This article features the findings of a new preprint study: Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming. It was published two days ago by BioRxiv. What is IgG4? Antibodies are one of the body’s first defenses against an…

The Fragility of the mRNA in the COVID-shots

Why do some people have severe adverse effects from the mRNA COVID shots and others do not? A study published in the Biophysical Journal explains. The body quickly destroys injected messenger RNAs. Moderna and Pfizer enclosed the mRNA inside a lipid nanoparticle (LPN) to prevent that. LPN also allows the large mRNAs to enter the…