The rise and rapid decline of 3 COVID vaccines’ effectiveness against severe disease and deaths

Posted on by Jesse Santiano, M.D.

The Lancet posted a retrospective study about the waning effectiveness of several COVID-19 vaccines among Sweden’s population.

The study group involved 842,974 matched pairs of vaccinated and unvaccinated individuals. The individuals were immunized with two doses of AstraZeneca (ChAdOx1 nCoV-19), Moderna (mRNA-1273), or Pfizer (BNT162b2).

Two critical endpoints were measured: symptomatic infections and severe Covid-19 (hospitalization or 30-day mortality after confirmed infection). They collected the data from 12 January to 4 October 2021.

The World Health Organization defines vaccine effectiveness as 50% and above.

Results

Vaccine effectiveness against symptomatic infection by age and gender

Age group

There is a progressive waning of vaccine effectiveness over time across all subgroups, but the rate of decline is faster in older age groups. At 61-120 days or 3-6 months, vaccine effectiveness declined to 50% among persons aged ≥ 80 years and 70% among frail individuals.

Gender

  • Men: No detectable effectiveness after six months – 17% effectiveness.
  • Women: 34% after six months

Effectiveness by Vaccine against Symptomatic Infection

Pfizer BNT162b2

Pfizer’s vaccine effectiveness against infection waned progressively from 92%  at day 15-30 to 47% at day 121-180, and from day 211 or seven months onwards, no effectiveness could be detected.

Moderna mRNA-1273

The effectiveness waned slightly slower for Moderna, estimated to be 59% from day 181 or six months onwards.

AstraZeneca (ChAdOx1 nCoV-19) 

AstraZeneca’s (ChAdOx1 nCoV-19) efficacy was generally lower and waned faster, with no effectiveness detected from four months.

Mixed vaccines or Heterologous

Effectiveness from heterologous AstraZeneca and Pfizer or Moderna was maintained from 121 days and onwards (66%).

Vaccine effectiveness was lower and waned faster among men and older individuals.

The figure below shows the waning of the vaccine effectiveness against symptomatic infection over time (all vaccines). Effectiveness peaked at days 15-30  and declined from days 31-60. From seven months onwards, there was no detectable effectiveness.

Source: Nordstrom et al.

Duration of vaccine effectiveness (any vaccine) against Hospitalization and Death

  1. 15-30 days  after the second dose – 89%
  2. Four to six months – 74%
  3. Six months onwards – 80 effective except for men, older frail individuals, and those with comorbidities.

The graph below shows vaccine effectiveness of 89% at days 13-30, which declined to 74% by four to six months. After six months onwards, there was no detectable effectiveness  (42%).

 

Source: Nordstrom et al.

Study Data about vaccine effectiveness against symptomatic COVID-19 infection, severe illness, and deaths

At 121-180 days, the vaccines are not effective for mean and all who are 50 – 64 years.

After 180 days or six months, the vaccines are ineffective in preventing symptomatic infection among all ages, gender, comorbidities, and frail individuals.

 

Source: Nordstrom et al.

Source: Nordstrom et al.

The following table shows that the vaccines’ effectiveness against hospitalization or death is only effective for up to six months.

The authors conclude that this study supports the use of booster shots.

My position is the opposite. Why would someone get a shot if it has been proven to lose effectiveness in less than a year? How often would a booster be needed? 19,886 have died after the shots, according to VAERS. How often would someone want to be exposed to the adverse reaction or possibly even die from the vaccines?

There is a way to prevent and treat COVID-19. An update to the I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 and An Update to FLCCC Treatment Protocol for the Delta Variant

People who recovered from COVID-19 may want to read this: Ten Studies showing a low risk of COVID-19 reinfection among unvaccinated.

People have personal reasons for why they take the shot. I present the research. People will have to make their risk-benefit analysis in making this personal decision.

 

Don’t Get Sick!

Knowledge about Covid-19 is rapidly evolving. Stay current by subscribing. Feel free to share and like.

If you find value in the articles, please consider donating to show your support.

Below are articles about the prevention and treatment protocols and their components.  

  1. Update to FLCCC Treatment Protocol for the Delta Variant
  2. COVID-19 Symptoms in the Vaccinated and Unvaccinated
  3. Update to the I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19
  4. What should the household do if someone has an Early COVID-19?
  5. The I-MASK+ for the Prophylaxis and Early Treatment Protocol of COVID-19
  6. The MATH+ Protocol Results in Greater Survival in Hospitalized COVID-19 Patients
  7. The I-RECOVER Management Protocol for Long Haul COVID-19 Syndrome
  8. What makes Ivermectin a kick-ass antiviral?
  9. The anti-COVID-19 properties of Quercetin
  10. Melatonin’s Multiple Actions Against COVID-19
  11. Povidone Iodine Works Great for the Prevention and Early Treatment of COVID-19!
  12. Vitamin C and COVID-19
  13. Zinc Deficiency Impairs the Immune System
  14. Adequate Vitamin D Prevents Severe COVID-19

Reference:  Nordström, Peter and Ballin, Marcel and Nordström, Anna, Effectiveness of Covid-19 Vaccination Against Risk of Symptomatic Infection, Hospitalization, and Death Up to 9 Months: A Swedish Total-Population Cohort Study. Available at SSRN: https://ssrn.com/abstract=3949410 or http://dx.doi.org/10.2139/ssrn.3949410

© 2018 – 2021 Asclepiades Medicine, L.L.C. All Rights Reserved
DrJesseSantiano.com does not provide medical advice, diagnosis, or treatment

As an Amazon Associate, I earn from qualifying purchases.

Comments are closed.