Otherwise known as the “Big C.” A diagnosis of cancer may feel like a death sentence. According to the Centers for Disease Control and Prevention., cancer is the number two cause of death in the U.S. in 2016 and 2017.
Ten leading causes of death: the United States 2016 and 2017
The Surveillance Research of the American Cancer Society estimated that the leading sites of new cancers and mortality in the U.S. for 2019 in men are the prostate (20%), lung and bronchus (13%), colon and rectum (9%), and urinary bladder (7%). For women, breast (30%), lung (13%), colon and rectum (9%), and uterine cancer (7%) are the most common.
The National Cancer Institute lists the most common in the following order: breast, followed by the lung, prostate, colon, and rectal.
The other cancers that are lower in incidence but not in significance are melanoma, pancreas, kidneys, Nnon-Hodgkin’s lymphoma, and leukemia.
The Metabolic Syndrome
Metabolic syndrome (MetS) is a group of five risk factors comprised of increased intraabdominal fat, high blood sugar, high blood pressure, low HDL, and high triglycerides. It can lead to strokes, heart attacks, and diabetes.
Studies that Associate Metabolic Syndrome with Cancer
This study, Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. Published in the New England Journal of Medicine, it followed more than 900,000 men and women for 16 years and concluded that,
“Increased body weight was associated with increased death rates for all cancers combined and for cancers at multiple specific sites.” “In both men and women, body-mass index was also significantly associated with higher rates of death due to cancer of the esophagus, colon and rectum, liver, gallbladder, pancreas, and kidney; the same was true for death due to non-Hodgkin’s lymphoma and multiple myeloma. Significant trends of increasing risk with higher body-mass-index values were observed for death from cancers of the stomach and prostate in men and for death from cancers of the breast, uterus, cervix, and ovary in women. ” They conluded that being overweight and obese in the United States could account for 14 percent of all deaths from cancer in men and 20 percent of those in women.
In the Aerobics Centre Longitudinal Study, published in the European Journal of Cancer entitled, Metabolic syndrome and risk of cancer mortality in men, 33,230 men aged 20-88 years were followed up for 14 years. The authors concluded that the presence of MetS or a higher number of MetS components was associated with a significantly higher risk for all-cause cancer mortality, as well as lung and colorectal cancer mortality.
This review from the International Journal of Biological Sciences, “The Link between the Metabolic Syndrome and Cancer,” discusses how obesity, dyslipidemia, and Type 2 Diabetes Mellitus (T2DM) are involved in the increased rate of cancer in the metabolic syndrome.
Related Readings:
- The Metabolic Syndrome
- Diseases Associated with the Metabolic Syndrome
- The 80/20 Rule Applied to Diseases
- Lung Diseases Associated with Metabolic Syndrome
- The Deadliest Diseases Associated with Metabolic Syndrome
- Abnormal Blood Clots and Metabolic Syndrome
- Eye Problems and Metabolic Syndrome
- Ear Problems and Metabolic Syndrome
- Metabolic Syndrome and the Pancreas
- Fasting and Exercise for Fatty Pancreas
- Fatty Liver and Metabolic Syndrome
- GERD/Heartburn and Metabolic Syndrome
- Crohn’s Disease and Metabolic Syndrome Part 1
- Crohn’s Disease and Metabolic Syndrome Part 2
- Gallbladder Diseases and Metabolic Syndrome
- Diseases of the Female Urinary and Reproductive System Associated with Metabolic Syndrome
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