SARS-CoV-2 Spike Protein Cause Red Blood cell Clumping and Ivermectin Prevents it

This article features a new study that adds proof that the spike protein of the SARS-CoV-2 virus increases the risk of blood clotting and that ivermectin can prevent it.

The authors are from the Aix-Marseille Université, a leading virology center in Marseille, France.

The research, SARS-CoV-2 Spike Protein Induces Hemagglutination: Implications for COVID-19 Morbidities and Therapeutics and for Vaccine Adverse Effects, found that the spike protein itself can cause hemagglutination. In this condition, the red blood cells stick to one another.

The microscopic image below from Wikipedia shows hemagglutination. Notice the red blood cells (brown colored) sticking to each other.

Previous studies have shown that the spike protein increases the agglutination or adhesion of other blood cells, like the platelets and the endothelial cells in the inner lining of the blood vessels. This results in clot formation, which explains the complications of COVID-19 and the adverse effects of the COVID jabs.

Clot formation in the arteries leads to heart attacks, strokes, loss of blood supply to the legs leading to amputation, brain fog, and kidney injuries, to mention a few.

The agglutination is due to the net positive charge of the spike protein and the negative charge of the red blood cells. Opposite charges attract, leading to the red blood cells adhering to the spike proteins. [2]

In contrast, negative charges on the red blood cells prevent them from sticking to one another.

Another reason for hemagglutination is the presence of glycans in the coronavirus and glycoproteins in the red blood cells causing a “deadly embrace.” [3]

Ivermectin was used in the study because a prior study has shown that it binds strongly to the glycan sites of SARS-CoV-2 to prevent hemagglutination.[4]

Method

In the experiment, the researchers used the spike protein from the Wuhan, Alpha,
Delta and Omicron B.1.1.529 lineages of SARS-CoV-2 mixed with human red blood cells (RBC).

Note: Remember that the spike protein in COVID “vaccines” is derived from the Wuhan variant, making this research’s results applicable to COVID jab injuries. The inclusion of the Omicron spike protein also makes this relevant to the present pandemic situation, as it is the dominant strain circulating.

Ivermectin is added to the red blood cells before and after exposure to the spike proteins. This mimics the prophylactic use and treatment with ivermectin.

Results

The investigators found that the spike protein from the four lineages of SARS-CoV-2 (Wuhan, Alpha, Delta, and Omicron) induced hemagglutination. Among the four, Omicron produced more hemagglutination more quickly than the three prior lineages. 

The authors also found that the Omicron has the highest positive charge, making it the most “attractive” to red blood cells.

The image below shows the electrostatic surface potential of SARS-CoV-2 spike trimers. Notice that the surface potential exponentially increases from the Wuhan to the Omicron lineage.

This finding raises a valid question. If the Omicron variant is the most conducive to hemagglutination, why is it that Omicron produces a less severe disease than the earlier variants?

The authors answered that increased binding affinities might result in the increased snagging of newly replicated virions on the host cells and viral snagging on non-infectious targets.[2]

The “snagging” may limit the ability of Omicron viruses from an infected alveolar cell to penetrate the alveoli in the lungs to infect an endothelial cell and enter the bloodstream. 

Ivermectin 

Part of the study was to know if ivermectin can prevent the red blood cells from sticking to each other and prevent severe COVID-19 and the complications of the COVID shots.

The reason they chose ivermectin is that ivermectin can bind to the glycan residues of the spike protein. A glycan is the carbohydrate portion of a glycoconjugate.

They found significant results. Ivermectin blocked hemagglutination when added to the red blood cells before spike protein was added and reversed hemagglutination when added afterward.

The results further add to the mechanistic explanation of why ivermectin works to prevent and treat COVID-19.

The screenshots below from the study showed hemagglutination of the red blood cells in Figure 1 (no teardrop visible) and  Figure 2 when hemagglutination did not occur (teardrop visible)

The image below shows hemagglutination (no teardrop)  induced by spike protein concentrations of 0.27, 0.53, 1.06, and 2.12 ng/µL for the Wuhan, Alpha, and Delta strains of SARS-CoV-2 and at spike protein concentrations of 0.07, 0.13, 0.27 and 0.53 ng/µL for Omicron.

It also shows the hemagglutination reversal (teardrop present) by ivermectin at concentrations of 1, 2, 4, and 8 µM added 30 min after RBCs and spike protein.

COVID-19 shots and hemagglutination

In their discussion, the authors raised their concern about the possibility of the COVID-19 injections causing hemagglutination and clot formation. This is because several studies by Cognetti et al., Ogata et al., and Röltgen et al. have shown that the  SARS-CoV-2 spike protein and S1 in serum or plasma have persisted for as long as 50 days following such vaccinations. 

As proof of the hemagglutination in COVID-vaccinated people, they referred to a study by Giovaninni et al. of 1,006 subjects who had adverse events after receiving a Pfizer/BioNTech or Moderna mRNA vaccination. In the study, 948 subjects had a significant degree of red blood cell aggregation in the blood. 

Ivermectin in protocols

The findings of this research support why ivermectin is part of several protocols for the prevention and treatment of COVID-19. 

• The FLCCC I-CARE Early COVID Treatment Protocol
• The I-PREVENT COVID Protection Protocol
• Dr. Peter McCullogh’s Early Treatment Protocol
• The late Dr. Vladimir Zelenko’s COVID-19 Treatment Protocol. 

The study is available as a preprint at medRxiv.

Don’t Get Sick!

Knowledge about Covid-19 is rapidly evolving. Stay current by subscribing. Feel free to share and like.

Related:

1. The NFL is giving their players IVERMECTIN as a prophylactic AND to prevent “positive” Covid tests
2. Japanese company announces Ivermectin has antiviral properties
3. City-wide use of Ivermectin lowered COVID-19 cases, hospitalizations, and deaths in Itajaí, Brazil
4. A new study shows a 100% decreased hospitalization rate with regular ivermectin use
5. Ivermectin prevents binding to human cells by blocking the spike protein
6. What makes Ivermectin a kick-ass antiviral?
7. IVMMETA.COM: A website of studies on Ivermectin’s efficacy
8. Ivermectin vs Remdesivir for COVID-19
9. Solved! The Ivermectin African Enigma
10. Ivermectin is effective against Influenza and Cold Virus In Vitro

References: