How I Learned to Make and Appreciate Powerful Natto

Originally published March 23, 2023. Fully updated March 28, 2026, with new fermentation technique, audio narration, and summary infographics. The health information has been reviewed for continued accuracy. 🎧 ▶️ Press the play button below to listen in English. 🎧 ▶️ 请按下面的播放按钮收听英文音频。 Introduction This article discusses how I made my first batch of natto. I…

How To Interpret The 10,800 FU Nattokinase Findings Safely

Audio updated March 31, 2026, for Apple device compatibility and a better infographic. 🎧 ▶️ Press the play button below to listen in English. A Helpful Guide for Readers Curious About the Popular 2022 Chinese Trial The 2022 Chinese study on 10,800 fibrinolytic units (FU) of nattokinase per day became very popular because it reported…

Could Nattokinase Be Useful In Preventing Alzheimer’s Dementia?

Alzheimer’s disease is a progressive brain disorder causing memory loss and cognitive decline, with no cure available. Research reveals that nasal health, including issues like chronic rhinosinusitis, may impact Alzheimer’s progression. The enzyme nattokinase shows potential in improving nasal conditions, possibly reducing inflammation linked to brain degeneration and early detection methods.

Low One-Hour Post-Prandial Blood Sugar after One Cup of Rice

Yesterday I posted that A High One-hour After-Meal Blood Sugar Test Can Lead to Several Deadly Conditions. In it, I showed that a blood sugar of more than 154.8 mg/dL or 8.6 mmol/L is highly predictive of the development not only of future type 2 or adult-onset diabetes but also cardiovascular disease and others, including higher all-cause mortality. …

Thoughts on Natto Making, Eating and Clean-up

This article contains suggestions on making natto. Natto is traditionally made from fermented soybeans cultured with the Bacillus Subtilis bacteria. Natto is the source of nattokinase which has many health benefits. Insulin Resistance and Atherosclerosis and the Nattokinase Solution The Outstanding Vascular Effects and Dose of Nattokinase Another Study shows Nattokinase can Destroy the S1…

An Unusual Case of Parkinsonism Improvement After Nattokinase Use

This article was updated with English, Spanish and Mandarin audio on November 21, 2025 🎧 Introducción en audio — Español (Latinoamérica) En este audio comentaremos un caso clínico donde una persona con síntomas de parkinsonismo experimentó mejoría después de usar nattokinasa. Revisaremos qué ocurrió, cómo se interpretan estos hallazgos y por qué este tipo de…

Laboratory Studies on Nattokinase and Abnormal Protein Aggregates

Audio updated March 29, 2026, for Apple device compatibility. This article was updated with audio on August 15, 2025. This article discusses research showing that nattokinase can dissolve amyloid and prion proteins. What are Amyloids and Prions? Both are abnormal proteins because they are misfolded. Proteins in various parts of the body serve multiple functions….

An Unusual Case of Prostate and Vascular Symptom Improvement With Nattokinase

This article was updated with audio on November 20, 2025. This article concerns a man with severe prostate pain and leg discoloration whose symptoms were relieved with nattokinase. The Problem A man in his mid-60s had two doses of the Pfizer shot in November 2021. He needed it to travel to attend a wedding. After…

Should You Take Nattokinase On An Empty Stomach?

Updated on November 25, 2025, with new English, Latin American Spanish, and Mandarin audio versions to help readers worldwide access this content and a brand new feature, the slideshow. 🎧 ▶️ Press the play button below to listen in English. 🇪🇸 Spanish (Latinoamérica) Hoy aprenderás si la nattokinasa debe tomarse en ayunas para una mejor…

How to Stop Bleeding if on Nattokinase

Nattokinase has anticoagulant properties. If you take nattokinase and have a cut, the bleeding may be more profuse than usual. It is the same as in any other drugs like aspirin or warfarin or newer ones like dabigatran. I have been taking nattokinase 2,000 FU every day since I have been writing about it. One night,…

Natto: An Application of the 80/20 Rule

This article was updated with audio on August 29, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. The 80/20 Rule The 80-20 rule, also known as the Pareto Principle, teaches us that a small effort often yields the majority of results. In health, this means just a few…

Nattokinase and Stroke Research: Understanding the Evidence

Updated on December 3, 2025, with new Latin American Spanish and Mandarin audio versions to help readers worldwide access this content. 🎧 ▶️ Press the play button below to listen in English.  🇪🇸 Spanish (Latinoamérica) En este audio descubrirás qué dice la evidencia más reciente sobre la nattokinasa y su posible papel en la prevención…

High-Dose Nattokinase and Its Potential Benefits for Blood Vessel and Lipid Health

Update:This article has been revised and updated on November 21, 2025, to meet current E-E-A-T standards. The information has been reviewed for accuracy, clarity, and medical safety to ensure readers receive high-quality, evidence-based guidance. English audio below. Press play to listen 🎧 Audio Introduction — Mandarin (中文普通话) 在这段音频中,我们将介绍高剂量纳豆激酶,以及研究中观察到的它对血管健康和血脂水平的潜在益处。我们会说明主要发现、如何理解这些结果,以及需要注意的安全事项。本内容仅供教育参考,不能替代专业医疗建议。 Introduction Recent research suggests that higher doses…

Nattokinase is Nontoxic with a High Safety Margin

This article was updated with audio on November 20, 2025. 🎧 ▶️ Press play below to listen. Your browser does not support the audio element. 🎧 Introducción en audio — Español (Latinoamérica) En este audio veremos lo que dicen los estudios sobre la seguridad de la nattokinasa y por qué se considera un suplemento con…

Nattokinase: Powerful Vascular Benefits and How to Dose It Right

 This article has been updated to include audio on November 20, 2025. About the AuthorJesse Santiano, M.D., is a retired physician trained in internal medicine and emergency medicine. He now focuses on preventive health education and evidence-based interpretation of cardiovascular, metabolic, and supplement research. This article summarizes published scientific findings and is for informational purposes…

Pandemic Lessons and Solutions

This article was updated with audio on September 3, 2025. Click on the play button below to listen. Your browser does not support the audio element. This article is a continuation of Dr. Alexandra Henrion Caude’s presentation at the PANDEMIC STRATEGIES, LESSONS, AND CONSEQUENCES in Stockholm, Sweden, on January 21 – 22, 2023. Läkaruppropet, a…

A Laboratory Study on Nattokinase and the S1 Spike Protein Fragment

Updated on November 21, 2025, with multilingual audio, new visual guides, and refined explanations to ensure the information is clear, current, and easy to follow. English audio below. Press play to listen Your browser does not support the audio element. 🎧 Introducción en audio — Español (Latinoamérica) En este audio hablaremos de un estudio de…

Laboratory Study Shows Nattokinase Can Break Down Spike Protein Fragments

This article was updated on November 21, 2025 with Spanish and Chinese audio, updated visuals, and improved explanations to reflect the most current understanding of the topic. About the AuthorJesse Santiano, M.D., is a retired physician specializing in internal medicine and emergency medicine. He now focuses on preventive health education and evidence-based analysis of emerging…