Spike Proteins, Blood Sugar at Inflammation: Alamin Ang Koneksyon

The Shocking Truth About Spike Proteins, Sugar And Inflammation

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The Shocking Truth About Spike Proteins, Sugar, And Inflammation

Summary: The Shocking Truth About Spike Proteins, Sugar, and Inflammation

This article explores the lasting presence of SARS-CoV-2 spike proteins in the body after COVID-19 infection or vaccination and how these remnants may contribute to chronic inflammation, autoimmunity, cancer, and excess deaths. The article also highlights the role of high blood sugar (hyperglycemia) in amplifying these harmful effects.

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1. Spike Proteins Stay in the Body

Post-Infection Evidence:

• Studies show that even after the virus is no longer detectable, fragments of spike proteins can remain in the blood, gut, and tissues for months to years.
• Research found spike proteins in:
  • Gut mucosa up to 7 months post-infection.
  • Blood and immune cells, even when viral RNA was gone.
  • Tissues of Long COVID patients.
• Some studies even suggest viral RNA can remain in the body for over 2 years.

Post-Vaccination Evidence:

• After receiving mRNA vaccines, spike proteins can be detected in the blood up to 60 days later.
• Spike protein has been found in lymph nodes, spleen, and immune cells weeks or months post-vaccination.
• mRNA and spike proteins can persist in tissues, possibly due to the lipid nanoparticle delivery system used in mRNA shots.
• A laboratory study also suggested the vaccine mRNA may enter human cell nuclei and be reverse transcribed.

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2. Persistent Spike Proteins Trigger Chronic Inflammation

Spike proteins bind to ACE2 receptors found in many tissues, leading to prolonged inflammation.

Inflammatory Effects by Organ System:

• Blood vessels: Spike proteins cause endothelial damage, increasing the risk for strokes and heart disease.
• Heart: Linked to myocarditis and pericarditis after mRNA vaccination and infection.
• Brain: Can cross the blood-brain barrier, activating brain immune cells (microglia) and causing “brain fog” and memory issues.
• Multiple organs: Contribute to kidney, liver, and gut inflammation seen in Long COVID.

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3. mRNA Vaccines and IgG4 Autoimmune Link

IgG4 Antibody Shift:

• Repeated mRNA shots may cause the immune system to switch from protective IgG1/IgG3 antibodies to IgG4, which is normally anti-inflammatory.
• While IgG4 can lower inflammation, it may also weaken the body’s ability to eliminate spike proteins and infected cells.

Autoimmune Reactions:

• Spike proteins may mimic human proteins, triggering autoimmune diseases like lupus, myocarditis, or rheumatoid arthritis.
• Evidence links IgG4 and persistent spike proteins with rising cases of autoimmune conditions post-injection.

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4. Spike Proteins and Cancer Risk

Reduced Immune Surveillance:

• IgG4 antibodies impair the immune system’s ability to detect and destroy abnormal or cancerous cells.
• Persistent spike proteins may therefore allow tumors to grow unchecked.

Direct Cancer Promotion:

• Spike proteins have been shown to activate oncogenic (cancer-promoting) pathways in lab studies.
• This may explain new or recurring cancers in some individuals post-infection or vaccination.

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5. Hyperglycemia: Fuel to the Fire

Chronic high blood sugar, whether from diabetes or a poor diet, worsens inflammation caused by spike proteins.

Mechanisms:

• AGEs and RAGEs: High blood sugar creates advanced glycation end products (AGEs) that bind to receptors (RAGEs), triggering inflammation.
• Vascular damage: Elevated glucose harms blood vessels and amplifies spike protein-induced damage.
• Immune suppression: Hyperglycemia impairs the immune response, making it harder to remove lingering spike proteins.

A Dangerous Cycle:

• Spike proteins themselves may cause insulin resistance and damage to insulin-producing cells, leading to high blood sugar.
• This creates a vicious cycle: spike proteins increase blood sugar, which worsens inflammation, which allows spike proteins to persist even longer.

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6. Explaining Excess Deaths Since 2021

Several studies and insurance data show a surge in all-cause mortality among adults aged 18–64 starting in 2021. The article proposes that:

• Persistent spike proteins continue to cause organ damage.
• Hyperglycemia fuels inflammation and weakens immunity.
• Cancer becomes more likely due to impaired surveillance and favorable growth conditions.
• Autoimmune diseases emerge or worsen.
• Poor resilience to infections leads to more complications, sepsis, and deaths.

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Takeaway Message

• Everyone—whether infected or vaccinated—may carry remnants of spike proteins.
• These can cause or worsen chronic inflammation, autoimmune issues, cancer, and other serious conditions.
• Hyperglycemia acts as an accelerant. It makes everything worse—whether from diet, diabetes, or metabolic disease.
• Actionable Advice: Keep blood sugar in check with:
  • Healthy diet
  • Exercise
  • Regular monitoring
  • Medical guidance if needed

Controlling blood sugar may reduce the risks associated with long-term exposure to spike proteins and protect overall health.

Don’t Get Sick!

Tagalog Summary: Nakakagulat na Katotohanan Tungkol sa Spike Proteins, Asukal, at Pamamaga

🧬 Pananatili ng Spike Proteins sa Katawan

• Pagkatapos ng COVID-19 Infection:
  • Kahit matagal nang gumaling, natagpuang may spike protein fragments pa rin sa dugo at bituka ng mga tao.
  • Sa ilang pag-aaral, tumagal ang spike proteins sa bituka hanggang 7 buwan pagkatapos ng impeksyon.
  • May mga kaso na nakita ang spike proteins sa loob ng mahigit 2 taon kahit negatibo na sa COVID test.
• Pagkatapos ng Pagbabakuna:
  • Sa mga nabakunahan gamit ang mRNA vaccines (Pfizer at Moderna), nakita pa rin ang spike proteins sa dugo hanggang 60 araw matapos ang injection.
  • Ipinakita ng biopsy na may spike proteins sa spleen at lymph nodes ilang linggo matapos bakunahan.
  • Posibleng pumasok ang mRNA sa loob ng cell nucleus ng tao, ayon sa isang pag-aaral sa liver cells.
• Paano Ito Nangyayari:
  • Ginagamit ang lipid nanoparticles para ihatid ang mRNA. Dahil dito, kumakalat ito sa maraming bahagi ng katawan at tumatagal kaysa inaasahan.

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🔥 Spike Proteins at Matagal na Pamamaga (Chronic Inflammation)

• Nagdudulot ng Pinsala ang Spike Protein Dahil:
  • Kumakabit ito sa ACE2 receptors sa puso, baga, bato, at daluyan ng dugo.
  • Pinipinsala nito ang endothelial cells, na nagiging sanhi ng pamamaga at pagbabara sa ugat.
  • Nagiging sanhi ng myocarditis at pericarditis (pamamaga ng puso).
  • Nakakatawid ito sa blood-brain barrier, kaya’t nai-uugnay ito sa “brain fog” at memory problems.
• Epekto sa Iba’t Ibang Organo:
  • Naiuugnay sa sakit sa bato, atay, at mga sintomas sa tiyan (gaya ng sa Long COVID).
  • Napatunayan din ng PET scan ang pamamaga sa puso ng ilang bakunadong indibidwal mahigit isang taon matapos ang bakuna.

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🛡️ mRNA Vaccine, IgG4, at Autoimmune Diseases

• Paglipat ng Antibody Type:
  • Sa mga paulit-ulit na mRNA injections, lumilipat ang katawan mula sa pro-inflammatory IgG1/IgG3 patungo sa IgG4—isang anti-inflammatory antibody.
  • Kahit nakakabawas ito ng pamamaga, pinahihina naman ang kakayahan ng katawan na alisin ang spike protein at infected cells.
• Mga Autoimmune na Sakit:
  • Ang spike protein ay maaaring gumaya sa normal na proteins ng katawan, na nagiging sanhi ng autoimmune diseases tulad ng lupus, arthritis, at myocarditis.
  • Lalo itong tumitindi kung may IgG4 antibody dominance.

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🧬 Spike Protein at Kanser

• Paghina ng Immune Surveillance:
  • Dahil sa IgG4, bumababa ang kakayahan ng immune system na tukuyin at sirain ang cancer cells.
  • Mas mataas ang panganib ng bagong kanser o pagbalik ng dati nang kanser.
• Direktang Pagpapalago ng Tumor:
  • Ang spike protein ay kayang i-activate ang mga oncogenic pathways, na pabor sa tumor growth ayon sa mga eksperimento sa laboratoryo.

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🍬 Hyperglycemia (Mataas na Asukal sa Dugo) Bilang Pampalala

• Pro-inflammatory Effects ng Mataas na Blood Sugar:
  • Nakakabuo ng AGEs (advanced glycation end-products) na nagti-trigger ng inflammation sa pamamagitan ng RAGE receptors.
  • Naglalabas ito ng mga cytokines gaya ng IL-6 at TNF-α, na nagpapalala sa pamamaga.
• Sira ang Endothelium:
  • Ang mataas na glucose ay sumisira sa lining ng mga ugat, at kapag may spike protein pa, lalo itong nakakasama.
  • Tumataas ang panganib sa stroke, heart attack, at kidney damage.
• Humihinang Immune System:
  • Binabawasan ng hyperglycemia ang kakayahan ng neutrophils at macrophages—kaya mas tumatagal ang spike protein sa katawan.

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🔁 Masamang Ikot: Spike Protein at Hyperglycemia

• Nagiging Sanhi ng Insulin Resistance:
  • Ang spike protein mismo ay maaaring sirain ang beta cells ng pancreas at magdulot ng insulin resistance, kahit sa mga dati’y hindi diabetic.
  • Nagiging cycle ito: spike protein → mataas na asukal → mas maraming inflammation → lalong tumatagal ang spike protein.
• Tumataas ang Risk sa Iba’t Ibang Sakit:
  • Kombinasyon ng spike protein at hyperglycemia ay nagpapalala sa:
    • Sakit sa puso
    • Sakit sa bato
    • Neuroinflammation

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📈 Bakit May Excess Deaths Mula 2021?

• Pagbilis ng Paglala ng Mga Sakit:
  • Chronic inflammation mula sa spike protein + hyperglycemia = mabilis na pagkasira ng organs.
  • Mas madalas ang atherosclerosis, heart failure, at iba pang sakit.
• Kanser at Impeksyon:
  • Tumataas ang kanser dahil sa weakened immune surveillance.
  • Mas madaling kapitan ng impeksyon ang mga taong may mataas na asukal sa dugo.
• Mga Artikulo na Sumusuporta sa Trend na Ito:
  • Lincoln National Insurance: 163% na pagtaas ng claims sa working age group (18–64) noong 2021.
  • CDC: Mas maraming namatay sa edad 25–54 mula 2021 kumpara sa mga taon bago ang pandemya.
  • Mas maraming namatay mula sa COVID ang nabakunahan kaysa hindi sa ilang bansa gaya ng Scotland.

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✅ Aral: Alagaan ang Blood Sugar

• Halos lahat ay na-expose sa spike protein—mula sa infection, bakuna, o pareho.
• Hindi natin alam kung sino pa ang may spike proteins sa katawan.
• Ngunit ang pagkontrol ng blood sugar ay kayang bawasan ang masamang epekto nito.

Mga Dapat Gawin:

• Kumain ng mababa ang glycemic index.
• Mag-ehersisyo araw-araw.
• I-monitor ang blood sugar regularly.
• Magpatingin sa doktor kung may sintomas ng diabetes o prediabetes.

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Huwag magkasakit! Gumamit ng kaalaman para manatiling malusog.

Related:

1. What happens to the heart after one year of COVID jab myocarditis?
2. Heart Inflammation After mRNA COVID Shots Proven by PET Scans
3. Persistence of mRNA Vaccine in the Heart
4. 13 ways that the SARS-CoV-2 spike protein causes damage
5. Human Organs Targeted by Covid-19
6. Another Study Confirms the Rise of IgG4 after the mRNA shots
7. mRNA COVID-19 Booster Shots Increase the Immunotolerant IgG4
8. The Devastating Effects of IgG4 after the mRNA COVID shots
9. Moderna and Pfizer COVID jabs Increase Anti-inflammatory IgG4
10. Pfizer mRNA shots Switch Antibodies to Non-Neutralizing IgG4
11. SAR-CoV-2 embedded in human cells, IgG4, Autoimmune Diseases and Cancer
12. Autoimmune conditions after COVID-19 and its injections
13. SAR-CoV-2 embedded in human cells, IgG4, Autoimmune Diseases and Cancer
14. The Complete Measure of Excess Deaths
15. Cardiac Arrhythmias Explain Excess Deaths
16. The Rise in Deaths Among Canadian Doctors
17. Lincoln National Insurance paid out 163% more for deaths of working people ages 18-64 in 2021
18. Pfizer COVID shot Lot Numbers with the most deaths
19. Excess deaths continue in 2022
20. Excess deaths in Scotland 2021
21. More COVID jabbed dead from COVID-19 than the unvaxxed in Scotland
22. Above-average deaths of 5 to 74 years old for the year 2021
23. US data: High numbers of autopsies done in 2021 among 15-64-year-olds.
24. CDC data shows higher deaths from 25-54 years old in 2021 compared to 2018-2020
25. 145 countries with higher COVID-19 cases and deaths after the COVID shots
26. Indiana life insurance CEO says deaths are up 40% among people ages 18-64
27. Vaccine-induced deaths in the US and Europe are way higher than the CDC reports!
28. German Analysis: The Higher the Vaccination Rate, the Higher the Excess Mortality

References:

1. Bansal et al. Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines. J Immunol November 15, 2021, 207 (10) 2405-2410
2. Rijkers GT, Weterings N, Obregon-Henao A, et al. Antigen Presentation of mRNA-Based and Virus-Vectored SARS-CoV-2 Vaccines. Vaccines (Basel). 2021;9(8):848. Published 2021 Aug 3. doi:10.3390/vaccines9080848
3. Kowarz E, Krutzke L, Reis J, et al. “Vaccine-Induced Covid-19 Mimicry” Syndrome: Splice reactions within the SARS-CoV-2 Spike open reading frame result in Spike protein variants that may cause thromboembolic events in patients immunized with vector-based vaccines. Research Square; 2021. DOI: 10.21203/rs.3.rs-558954/v1
4. Ogata AF. et al. Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients [published online ahead of print, 2021 May 20]. Clin Infect Dis. 2021;ciab465. doi:10.1093/cid/ciab465
5. Hervier B, Ribon M, Tarantino N, Mussard J, Breckler M, Vieillard V, Amoura Z, Steinle A, Klein R, Kötter I, Decker P. Increased Concentrations of Circulating Soluble MHC Class I-Related Chain A (sMICA) and sMICB and Modulation of Plasma Membrane MICA Expression: Potential Mechanisms and Correlation With Natural Killer Cell Activity in Systemic Lupus Erythematosus. Front Immunol. 2021 May 3;12:633658. doi: 10.3389/fimmu.2021.633658. PMID: 34012432; PMCID: PMC8126610.
6. Salih, Helmut & Goehlsdorf, Dennis & Steinle, Alexander. (2006). Salih HR, Goehlsdorf D, Steinle A. Release of MICB molecules by tumor cells: mechanism and soluble MICB in sera of cancer patients. Hum Immunol 67: 188-195. Human immunology. 67. 188-95. 10.1016/j.humimm.2006.02.008.
7. Edgar JR. Q&A: What are exosomes, exactly?. BMC Biol. 2016;14:46. Published 2016 Jun 13. doi:10.1186/s12915-016-0268-z
8. Raposo G, Nijman HW, Stoorvogel W, Liejendekker R, Harding CV, Melief CJ, Geuze HJ. B lymphocytes secrete antigen-presenting vesicles. J Exp Med. 1996 Mar 1;183(3):1161-72. doi: 10.1084/jem.183.3.1161. PMID: 8642258; PMCID: PMC2192324.
9. Nuovo, G.J. et al. (2021) Endothelial cell damage is the central part of COVID-19 and a mouse model induced by injection of the S1 subunit of the spike protein. Ann. Diagn. Pathol. 51, 151682, https://doi.org/10.1016/j.anndiagpath.2020.151682
10. Gu, T. et al. (2020) Cytokine signature induced by SARS-CoV-2 spike protein in a mouse model. Front. Immunol. 11, 621441,
11. Aboudounya MM, Heads RJ. COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation. Mediators Inflamm. 2021 Jan 14;2021:8874339. doi: 10.1155/2021/8874339. PMID: 33505220; PMCID: PMC7811571.
12. Shirato K, Kizaki T. SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages. Heliyon. 2021 Feb 2;7(2):e06187. doi: 10.1016/j.heliyon.2021.e06187. PMID: 33644468; PMCID: PMC7887388. https://pubmed.ncbi.nlm.nih.gov/33644468/
13. Suzuki YJ, et al. SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines. Vaccines (Basel). 2021;9(1):36. Published 2021 Jan 11. doi:10.3390/vaccines9010036
14. Cao, X. et al. (2021) Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice. FASEB J. 35, e21801
15. Biering et al. SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling. bioRxiv 2021.12.10.472112
16. Avolio E et al.  The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signaling: a potential non-infective mechanism of COVID-19 microvascular disease. Clin Sci (Lond). 2021 Dec 22;135(24):2667-2689. doi: 10.1042/CS20210735. PMID: 34807265; PMCID: PMC8674568.
17. Lei, Y. et al. SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2. Circulation Research. 2021;128:1323–1326
18. Grobbelaar, L.M. et al. (2021) SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19. Biosci. Rep. 41 (8)
19. Patterson B. et al. Persistence of SARS CoV-2 S1 Protein in CD16+ Monocytes in Post-Acute Sequelae of COVID-19 (PASC) Up to 15 Months Post-Infection. bioRxiv 2021.06.25.449905
20. Yu J, Yuan X, Chen H, Chaturvedi S, Braunstein EM, Brodsky RA. Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition. Blood. 2020.
21. Nyström et al. Amyloidogenesis of SARS-CoV-2 Spike Protein. bioRxiv 2021.12.16.472920. 
22. Idrees D, Kumar V. SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration. Biochem Biophys Res Commun. 2021 May 21;554:94-98. doi: 10.1016/j.bbrc.2021.03.100. Epub 2021 Mar 24. PMID: 33789211; PMCID: PMC7988450
23. Nunez-Castilla, J et al. Spike mimicry of thrombopoietin may induce thrombocytopenia in COVID-19. bioRxiv 2021.08.10.455737
24. Ehrenfeld M et al. Covid-19 and autoimmunity. Autoimmun Rev. 2020;19:102597.
25. Kanduc D, Shoenfeld Y. On the molecular determinants of the SARS-CoV-2 attack. Clin Immunol. 2020;215. 
26. Vojdani A, Kharrazian D. Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases. Clin Immunol. 2020;217:108480
27. Chen Y, Xu Z, Wang P, Li XM, Shuai ZW, Ye DQ, Pan HF. New-onset autoimmune phenomena post-COVID-19 vaccination. Immunology. 2021 Dec 27. doi: 10.1111/imm.13443. Epub ahead of print. PMID: 34957554.
28. Jiang H, Mei YF. SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro. Viruses. 2021;13(10):2056. Published 2021 Oct 13. doi:10.3390/v13102056
29. BRCA1 gene. Medline [website]
30. Mirza-Aghazadeh-Attari M, et al.  53BP1: A key player of DNA damage response with critical functions in cancer. DNA Repair (Amst). 2019 Jan;73:110-119. doi: 10.1016/j.dnarep.2018.11.008. Epub 2018 Nov 20. PMID: 30497961.
31. Segal, Y., Shoenfeld, Y. Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction. Cell Mol Immunol 15, 586–594 (2018). https://doi.org/10.1038/cmi.2017.151

Huwag Magkasakit! Don’t Get Sick!

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